Bruce M. Spiegelman

Research interests

Publications

• A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

  Nature · 2012 · https://doi.org/10.1038/nature10777

• PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

  Nature Genetics · 2003 · https://doi.org/10.1038/ng1180

• Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1

  Cell · 1999 · https://doi.org/10.1016/s0092-8674(00)80611-x

• A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

  Cell · 1998 · https://doi.org/10.1016/s0092-8674(00)81410-5

• Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance

  Science · 1993 · https://doi.org/10.1126/science.7678183

Current projects

No projects listed.