Gregg L. Semenza

Researcher Next ID · RN-002343

Researcher · Biochemistry, Genetics and Molecular Biology

Rome, Italy

Not currently recruitingFunding unknown

Research interests

Biochemistry, Genetics and Molecular Biology

Medicine

Cancer, Hypoxia, and Metabolism

High Altitude and Hypoxia

Mitochondrial Function and Pathology

Angiogenesis and VEGF in Cancer

Adipose Tissue and Metabolism

Hypoxia-Inducible Factors in Physiology and Medicine
Cell · 2012 · https://doi.org/10.1016/j.cell.2012.01.021
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
Cell Metabolism · 2006 · https://doi.org/10.1016/j.cmet.2006.02.002
Targeting HIF-1 for cancer therapy
Nature reviews. Cancer · 2003 · https://doi.org/10.1038/nrc1187
Activation of Vascular Endothelial Growth Factor Gene Transcription by Hypoxia-Inducible Factor 1
Molecular and Cellular Biology · 1996 · https://doi.org/10.1128/mcb.16.9.4604
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
Proceedings of the National Academy of Sciences · 1995 · https://doi.org/10.1073/pnas.92.12.5510

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