Jeffrey L. Wrana

Researcher Next ID · RN-004290

Researcher · Biochemistry, Genetics and Molecular Biology

Toronto, Canada

Not currently recruitingFunding unknown

Research interests

Biochemistry, Genetics and Molecular Biology

TGF-β signaling in diseases

Hippo pathway signaling and YAP/TAZ

Cancer-related gene regulation

Epigenetics and DNA Methylation

Nutrition, Genetics, and Disease

Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration
Cell · 2012 · https://doi.org/10.1016/j.cell.2012.11.024
Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation
Molecular Cell · 2000 · https://doi.org/10.1016/s1097-2765(00)00134-9
The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling
Cell · 1997 · https://doi.org/10.1016/s0092-8674(00)80303-7
Mechanism of activation of the TGF-β receptor
Nature · 1994 · https://doi.org/10.1038/370341a0
TGFβ signals through a heteromeric protein kinase receptor complex
Cell · 1992 · https://doi.org/10.1016/0092-8674(92)90395-s

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