Kun‐Liang Guan

Researcher Next ID · RN-005067

Researcher · Biochemistry, Genetics and Molecular Biology

Hangzhou, China

Not currently recruitingFunding unknown

Research interests

Biochemistry, Genetics and Molecular Biology

Medicine

Hippo pathway signaling and YAP/TAZ

PI3K/AKT/mTOR signaling in cancer

Cancer, Hypoxia, and Metabolism

Protein Kinase Regulation and GTPase Signaling

Autophagy in Disease and Therapy

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Nature Cell Biology · 2011 · https://doi.org/10.1038/ncb2152
Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
Cancer Cell · 2011 · https://doi.org/10.1016/j.ccr.2010.12.014
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
Genes & Development · 2007 · https://doi.org/10.1101/gad.1602907
TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
Cell · 2003 · https://doi.org/10.1016/s0092-8674(03)00929-2
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
Nature Cell Biology · 2002 · https://doi.org/10.1038/ncb839

No projects listed.