Ricardo T. Gazzinelli

Researcher Next ID · RN-006079

Researcher · Medicine

Belo Horizonte, Brazil

Not currently recruitingFunding unknown

Research interests

Medicine

Immunology and Microbiology

Trypanosoma species research and implications

Research on Leishmaniasis Studies

Toxoplasma gondii Research Studies

Immune Cell Function and Interaction

Malaria Research and Control

Regulation and Function of T-Cell-Mediated Immunity duringToxoplasma gondiiInfection
Clinical Microbiology Reviews · 1998 · https://doi.org/10.1128/cmr.11.4.569
In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-γ and TNF-α
The Journal of Immunology · 1996 · https://doi.org/10.4049/jimmunol.157.2.798
Parasite-induced IL-12 stimulates early IFN- gamma synthesis and resistance during acute infection with Toxoplasma gondii .
The Journal of Immunology · 1994 · https://doi.org/10.4049/jimmunol.153.6.2533
Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming.
Proceedings of the National Academy of Sciences · 1993 · https://doi.org/10.1073/pnas.90.21.10188
Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts.
Proceedings of the National Academy of Sciences · 1993 · https://doi.org/10.1073/pnas.90.13.6115

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