David M. Hockenbery

Researcher Next ID · RN-009018

Researcher · Biochemistry, Genetics and Molecular Biology

Cape Town, South Africa

Not currently recruitingFunding unknown

Research interests

Biochemistry, Genetics and Molecular Biology

Medicine

Cell death mechanisms and regulation

Mitochondrial Function and Pathology

Hematopoietic Stem Cell Transplantation

Cancer, Hypoxia, and Metabolism

Cancer-related Molecular Pathways

Bcl-2 functions in an antioxidant pathway to prevent apoptosis
Cell · 1993 · https://doi.org/10.1016/0092-8674(93)80066-n
BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.
Proceedings of the National Academy of Sciences · 1991 · https://doi.org/10.1073/pnas.88.16.6961
bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
Cell · 1991 · https://doi.org/10.1016/0092-8674(91)90361-2
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
Nature · 1990 · https://doi.org/10.1038/348334a0
Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.
The Journal of Immunology · 1990 · https://doi.org/10.4049/jimmunol.144.9.3602

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