Lu Wang

Research interests

Publications

• N7-methylguanosine tRNA modification promotes esophageal squamous cell carcinoma tumorigenesis via the RPTOR/ULK1/autophagy axis

  Nature Communications · 2022 · https://doi.org/10.1038/s41467-022-29125-7

• Comprehensive Molecular Characterization of Salivary Duct Carcinoma Reveals Actionable Targets and Similarity to Apocrine Breast Cancer

  Clinical Cancer Research · 2016 · https://doi.org/10.1158/1078-0432.ccr-16-0637

• Cabozantinib in patients with advanced RET-rearranged non-small-cell lung cancer: an open-label, single-centre, phase 2, single-arm trial

  The Lancet Oncology · 2016 · https://doi.org/10.1016/s1470-2045(16)30562-9

• Broad, Hybrid Capture–Based Next-Generation Sequencing Identifies Actionable Genomic Alterations in Lung Adenocarcinomas Otherwise Negative for Such Alterations by Other Genomic Testing Approaches

  Clinical Cancer Research · 2015 · https://doi.org/10.1158/1078-0432.ccr-14-2683

• Alternative transcription initiation leads to expression of a novel ALK isoform in cancer

  Nature · 2015 · https://doi.org/10.1038/nature15258

• A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations

  Nature Genetics · 2014 · https://doi.org/10.1038/ng.2969

• Gene targeting using the Agrobacterium tumefaciens-mediated CRISPR-Cas system in rice

  Rice · 2014 · https://doi.org/10.1186/s12284-014-0005-6

• Rb suppresses human cone-precursor-derived retinoblastoma tumours

  Nature · 2014 · https://doi.org/10.1038/nature13813

• Rationale for co-targeting IGF-1R and ALK in ALK fusion–positive lung cancer

  Nature Medicine · 2014 · https://doi.org/10.1038/nm.3667

• Rationale for co-targeting IGF-1R and ALK in ALK fusion–positive lung cancer

  Nature Medicine · 2014 · https://doi.org/10.1038/nm.3667

• The genomics of selection in dogs and the parallel evolution between dogs and humans

  Nature Communications · 2013 · https://doi.org/10.1038/ncomms2814

• Pilot: Passive Device-Free Indoor Localization Using Channel State Information

  Journal · 2013 · https://doi.org/10.1109/icdcs.2013.49

• Response to Cabozantinib in Patients with RET Fusion-Positive Lung Adenocarcinomas

  Cancer Discovery · 2013 · https://doi.org/10.1158/2159-8290.cd-13-0035

• Population‐Based Incidence and Prevalence of Systemic Lupus Erythematosus: The Michigan Lupus Epidemiology and Surveillance Program

  Arthritis & Rheumatology · 2013 · https://doi.org/10.1002/art.38238

• HIV prevalence in China: integration of surveillance data and a systematic review

  The Lancet Infectious Diseases · 2013 · https://doi.org/10.1016/s1473-3099(13)70245-7

• Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1

  Proceedings of the National Academy of Sciences · 2012 · https://doi.org/10.1073/pnas.1203530109

• Optimization of Dosing for EGFR-Mutant Non–Small Cell Lung Cancer with Evolutionary Cancer Modeling

  Science Translational Medicine · 2011 · https://doi.org/10.1126/scitranslmed.3002356

• Identification of a novel, recurrent HEY1‐NCOA2 fusion in mesenchymal chondrosarcoma based on a genome‐wide screen of exon‐level expression data

  Genes Chromosomes and Cancer · 2011 · https://doi.org/10.1002/gcc.20937

• The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma

  Nature Genetics · 2011 · https://doi.org/10.1038/ng.855

• PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas

  Genes & Development · 2010 · https://doi.org/10.1101/gad.1972310

• High-throughput genotyping by whole-genome resequencing

  Genome Research · 2009 · https://doi.org/10.1101/gr.089516.108

• MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib

  Proceedings of the National Academy of Sciences · 2007 · https://doi.org/10.1073/pnas.0710370104

• Role of the Cytosolic Chaperones Hsp70 and Hsp90 in Maturation of the Cardiac Potassium Channel hERG

  Circulation Research · 2003 · https://doi.org/10.1161/01.res.0000079028.31393.15

Current projects

No projects listed.