Johan Ericsson

Research interests

Publications

• Regulation of lipogenesis by cyclin-dependent kinase 8–mediated control of SREBP-1

  Journal of Clinical Investigation · 2012 · https://doi.org/10.1172/jci61462

• TRAF6 ubiquitinates TGFβ type I receptor to promote its cleavage and nuclear translocation in cancer

  Nature Communications · 2011 · https://doi.org/10.1038/ncomms1332

• Increased Lipogenesis, Induced by AKT-mTORC1-RPS6 Signaling, Promotes Development of Human Hepatocellular Carcinoma

  Gastroenterology · 2010 · https://doi.org/10.1053/j.gastro.2010.12.006

• A Phosphorylation Cascade Controls the Degradation of Active SREBP1

  Journal of Biological Chemistry · 2009 · https://doi.org/10.1074/jbc.m807906200

• Fatty Acid Synthase Gene Is Up-regulated by Hypoxia via Activation of Akt and Sterol Regulatory Element Binding Protein-1

  Cancer Research · 2008 · https://doi.org/10.1158/0008-5472.can-07-2489

• SREBP in signal transduction: cholesterol metabolism and beyond

  Current Opinion in Cell Biology · 2007 · https://doi.org/10.1016/j.ceb.2007.02.004

• Phosphorylation and Ubiquitination of the Transcription Factor Sterol Regulatory Element-binding Protein-1 in Response to DNA Binding

  Journal of Biological Chemistry · 2006 · https://doi.org/10.1074/jbc.m604983200

• The DNA Binding Activities of Smad2 and Smad3 Are Regulated by Coactivator-mediated Acetylation

  Journal of Biological Chemistry · 2006 · https://doi.org/10.1074/jbc.m607868200

• Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCFFbw7

  Cell Metabolism · 2005 · https://doi.org/10.1016/j.cmet.2005.04.010

• The Balance between Acetylation and Deacetylation Controls Smad7 Stability

  Journal of Biological Chemistry · 2005 · https://doi.org/10.1074/jbc.m503134200

• YY1 inhibits the activation of the p53 tumor suppressor in response to genotoxic stress

  Proceedings of the National Academy of Sciences · 2004 · https://doi.org/10.1073/pnas.0402283101

• Platelet-derived Growth Factor Stimulates Membrane Lipid Synthesis Through Activation of Phosphatidylinositol 3-Kinase and Sterol Regulatory Element-binding Proteins

  Journal of Biological Chemistry · 2004 · https://doi.org/10.1074/jbc.m405924200

• Nuclear Factor YY1 Inhibits Transforming Growth Factor β- and Bone Morphogenetic Protein-Induced Cell Differentiation

  Molecular and Cellular Biology · 2003 · https://doi.org/10.1128/mcb.23.13.4494-4510.2003

• Coactivator-Dependent Acetylation Stabilizes Members of the SREBP Family of Transcription Factors

  Molecular and Cellular Biology · 2003 · https://doi.org/10.1128/mcb.23.7.2587-2599.2003

• Control of Smad7 Stability by Competition between Acetylation and Ubiquitination

  Molecular Cell · 2002 · https://doi.org/10.1016/s1097-2765(02)00639-1

• Sterols and Isoprenoids: Signaling Molecules Derived from the Cholesterol Biosynthetic Pathway

  Annual Review of Biochemistry · 1999 · https://doi.org/10.1146/annurev.biochem.68.1.157

• Identification of Glycerol-3-phosphate Acyltransferase as an Adipocyte Determination and Differentiation Factor 1- and Sterol Regulatory Element-binding Protein-responsive Gene

  Journal of Biological Chemistry · 1997 · https://doi.org/10.1074/jbc.272.11.7298

• Sterol regulatory element binding protein binds to a cis element in the promoter of the farnesyl diphosphate synthase gene.

  Proceedings of the National Academy of Sciences · 1996 · https://doi.org/10.1073/pnas.93.2.945

• Branch-point reactions in the biosynthesis of cholesterol, dolichol, ubiquinone and prenylated proteins

  Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · 1994 · https://doi.org/10.1016/0005-2760(94)90200-3

Current projects

No projects listed.