Yi Chen

Research interests

Publications

• Tissue-resident Lachnospiraceae family bacteria protect against colorectal carcinogenesis by promoting tumor immune surveillance

  Cell Host & Microbe · 2023 · https://doi.org/10.1016/j.chom.2023.01.013

• Mitochondrial Sirtuin 3: New emerging biological function and therapeutic target

  Theranostics · 2020 · https://doi.org/10.7150/thno.45922

• Phytoplankton response to polystyrene microplastics: Perspective from an entire growth period

  Chemosphere · 2018 · https://doi.org/10.1016/j.chemosphere.2018.05.170

• Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors

  Cell · 2018 · https://doi.org/10.1016/j.cell.2018.08.058

• Nanoparticle Superlattices: The Roles of Soft Ligands

  Advanced Science · 2017 · https://doi.org/10.1002/advs.201700179

• Aptamer-Conjugated Graphene Quantum Dots/Porphyrin Derivative Theranostic Agent for Intracellular Cancer-Related MicroRNA Detection and Fluorescence-Guided Photothermal/Photodynamic Synergetic Therapy

  ACS Applied Materials & Interfaces · 2016 · https://doi.org/10.1021/acsami.6b13150

• Acoustically Propelled Nanomotors for Intracellular siRNA Delivery

  ACS Nano · 2016 · https://doi.org/10.1021/acsnano.6b01415

• Long Circulation Red‐Blood‐Cell‐Mimetic Nanoparticles with Peptide‐Enhanced Tumor Penetration for Simultaneously Inhibiting Growth and Lung Metastasis of Breast Cancer

  Advanced Functional Materials · 2016 · https://doi.org/10.1002/adfm.201504780

• DNA Compatible Multistep Synthesis and Applications to DNA Encoded Libraries

  Bioconjugate Chemistry · 2015 · https://doi.org/10.1021/acs.bioconjchem.5b00239

• Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates

  Proceedings of the National Academy of Sciences · 2014 · https://doi.org/10.1073/pnas.1322937111

• Investigation of the physicochemical properties and catalytic activities of Ce 0.67 M 0.33 O 2 (M = Zr 4+ , Ti 4+ , Sn 4+ ) solid solutions for NO removal by CO

  Catalysis Science & Technology · 2012 · https://doi.org/10.1039/c2cy20610b

• Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

  Nature Nanotechnology · 2012 · https://doi.org/10.1038/nnano.2012.73

• Rapid Discovery of Potent siRNA-Containing Lipid Nanoparticles Enabled by Controlled Microfluidic Formulation

  Journal of the American Chemical Society · 2012 · https://doi.org/10.1021/ja301621z

• Facile Synthesis of Monodisperse Superparamagnetic Fe3O4 Core@hybrid@Au Shell Nanocomposite for Bimodal Imaging and Photothermal Therapy

  Advanced Materials · 2011 · https://doi.org/10.1002/adma.201103521

• From molecular to macroscopic via the rational design of a self-assembled 3D DNA crystal

  Nature · 2009 · https://doi.org/10.1038/nature08274

• DNA Nanotubes as Combinatorial Vehicles for Cellular Delivery

  Biomacromolecules · 2008 · https://doi.org/10.1021/bm800479e

• Self-Assembly of Hexagonal DNA Two-Dimensional (2D) Arrays

  Journal of the American Chemical Society · 2005 · https://doi.org/10.1021/ja0541938

• A DNAzyme That Walks Processively and Autonomously along a One‐Dimensional Track

  Angewandte Chemie International Edition · 2005 · https://doi.org/10.1002/anie.200500703

• A DNA Nanomachine Based on a Duplex–Triplex Transition

  Angewandte Chemie International Edition · 2004 · https://doi.org/10.1002/anie.200460789

• An Autonomous DNA Nanomotor Powered by a DNA Enzyme

  Angewandte Chemie International Edition · 2004 · https://doi.org/10.1002/anie.200453779

• Activation by IKKα of a Second, Evolutionary Conserved, NF-κB Signaling Pathway

  Science · 2001 · https://doi.org/10.1126/science.1062677

• NAK is an IκB kinase-activating kinase

  Nature · 2000 · https://doi.org/10.1038/35008109

• Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase

  Nature · 2000 · https://doi.org/10.1038/47520

• Positive and Negative Regulation of IκB Kinase Activity Through IKKβ Subunit Phosphorylation

  Science · 1999 · https://doi.org/10.1126/science.284.5412.309

• JNK2 and IKKβ Are Required for Activating the Innate Response to Viral Infection

  Immunity · 1999 · https://doi.org/10.1016/s1074-7613(00)80146-6

• Disruption of the p70s6k/p85s6k gene reveals a small mouse phenotype and a new functional S6 kinase

  The EMBO Journal · 1998 · https://doi.org/10.1093/emboj/17.22.6649

• Direct Phosphorylation of IκB by IKKα and IKKβ: Discrimination Between Free and NF-κB-Bound Substrate

  Science · 1998 · https://doi.org/10.1126/science.281.5381.1360

Current projects

No projects listed.