Vsevolod Katritch

Research interests

Publications

• Computational approaches streamlining drug discovery

  Nature · 2023 · https://doi.org/10.1038/s41586-023-05905-z

• Synthon-based ligand discovery in virtual libraries of over 11 billion compounds

  Nature · 2021 · https://doi.org/10.1038/s41586-021-04220-9

• Crystal Structure of the Human Cannabinoid Receptor CB2

  Cell · 2019 · https://doi.org/10.1016/j.cell.2018.12.011

• Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

  Nature · 2015 · https://doi.org/10.1038/nature14656

• Structure of the human P2Y12 receptor in complex with an antithrombotic drug

  Nature · 2014 · https://doi.org/10.1038/nature13083

• Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography

  Nature Communications · 2014 · https://doi.org/10.1038/ncomms4309

• Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator

  Science · 2014 · https://doi.org/10.1126/science.1249489

• Allosteric sodium in class A GPCR signaling

  Trends in Biochemical Sciences · 2014 · https://doi.org/10.1016/j.tibs.2014.03.002

• Generic GPCR residue numbers – aligning topology maps while minding the gaps

  Trends in Pharmacological Sciences · 2014 · https://doi.org/10.1016/j.tips.2014.11.001

• Molecular control of δ-opioid receptor signalling

  Nature · 2014 · https://doi.org/10.1038/nature12944

• Structural Basis for Molecular Recognition at Serotonin Receptors

  Science · 2013 · https://doi.org/10.1126/science.1232807

• Serial Femtosecond Crystallography of G Protein–Coupled Receptors

  Science · 2013 · https://doi.org/10.1126/science.1244142

• Structure of the human smoothened receptor bound to an antitumour agent

  Nature · 2013 · https://doi.org/10.1038/nature12167

• Structural Features for Functional Selectivity at Serotonin Receptors

  Science · 2013 · https://doi.org/10.1126/science.1232808

• Fusion Partner Toolchest for the Stabilization and Crystallization of G Protein-Coupled Receptors

  Structure · 2012 · https://doi.org/10.1016/j.str.2012.04.010

• Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions

  Science · 2012 · https://doi.org/10.1126/science.1219218

• Biased Signaling Pathways in β 2 -Adrenergic Receptor Characterized by 19 F-NMR

  Science · 2012 · https://doi.org/10.1126/science.1215802

• Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic

  Nature · 2012 · https://doi.org/10.1038/nature11085

• Structure of the human κ-opioid receptor in complex with JDTic

  Nature · 2012 · https://doi.org/10.1038/nature10939

• Structure-Function of the G Protein–Coupled Receptor Superfamily

  The Annual Review of Pharmacology and Toxicology · 2012 · https://doi.org/10.1146/annurev-pharmtox-032112-135923

• Structure of an Agonist-Bound Human A 2A Adenosine Receptor

  Science · 2011 · https://doi.org/10.1126/science.1202793

• Structure of the human histamine H1 receptor complex with doxepin

  Nature · 2011 · https://doi.org/10.1038/nature10236

• Diversity and modularity of G protein-coupled receptor structures

  Trends in Pharmacological Sciences · 2011 · https://doi.org/10.1016/j.tips.2011.09.003

• Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists

  Science · 2010 · https://doi.org/10.1126/science.1194396

• Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

  Science · 2010 · https://doi.org/10.1126/science.1197410

Current projects

No projects listed.