Ultan McDermott

Research interests

Publications

• Image-based consensus molecular subtype (imCMS) classification of colorectal cancer using deep learning

  Gut · 2020 · https://doi.org/10.1136/gutjnl-2019-319866

• ctDNA monitoring using patient-specific sequencing and integration of variant reads

  Science Translational Medicine · 2020 · https://doi.org/10.1126/scitranslmed.aaz8084

• Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0086-z

• A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia

  Cell Reports · 2016 · 10.1016/j.celrep.2016.09.079

• A Landscape of Pharmacogenomic Interactions in Cancer

  Cell · 2016 · https://doi.org/10.1016/j.cell.2016.06.017

• Mutational signatures of ionizing radiation in second malignancies

  Nature Communications · 2016 · https://doi.org/10.1038/ncomms12605

• The evolutionary history of lethal metastatic prostate cancer

  Nature · 2015 · https://doi.org/10.1038/nature14347

• Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

  Nature Genetics · 2015 · https://doi.org/10.1038/ng.3221

• Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

  Cell · 2015 · https://doi.org/10.1016/j.cell.2015.03.053

• COSMIC: exploring the world's knowledge of somatic mutations in human cancer

  Nucleic Acids Research · 2014 · https://doi.org/10.1093/nar/gku1075

• Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

  eLife · 2014 · https://doi.org/10.7554/elife.02935

• Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

  Science · 2014 · https://doi.org/10.1126/science.1251343

• Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma

  Nature Communications · 2014 · 10.1038/ncomms6712

• Signatures of mutational processes in human cancer

  Nature · 2013 · 10.1038/nature12477

• MED12 Controls the Response to Multiple Cancer Drugs through Regulation of TGF-β Receptor Signaling

  Cell · 2012 · https://doi.org/10.1016/j.cell.2012.10.035

• Systematic identification of genomic markers of drug sensitivity in cancer cells

  Nature · 2012 · 10.1038/nature11005

• Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells

  Nucleic Acids Research · 2012 · 10.1093/nar/gks1111

• Development and Independent Validation of a Prognostic Assay for Stage II Colon Cancer Using Formalin-Fixed Paraffin-Embedded Tissue

  Journal of Clinical Oncology · 2011 · https://doi.org/10.1200/jco.2011.35.4498

Current projects

No projects listed.