Joshua Armenia

Research interests

Publications

• The repertoire of mutational signatures in human cancer

  Nature · 2020 · https://doi.org/10.1038/s41586-020-1943-3

• Pan-cancer analysis of whole genomes

  Nature · 2020 · https://doi.org/10.1038/s41586-020-1969-6

• Comprehensive molecular characterization of mitochondrial genomes in human cancers

  Nature Genetics · 2020 · https://doi.org/10.1038/s41588-019-0557-x

• The landscape of viral associations in human cancers

  Nature Genetics · 2020 · https://doi.org/10.1038/s41588-019-0558-9

• Genomic correlates of clinical outcome in advanced prostate cancer

  Proceedings of the National Academy of Sciences · 2019 · https://doi.org/10.1073/pnas.1902651116

• Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

  Cell · 2018 · 10.1016/j.cell.2018.03.034

• Genomic and Functional Approaches to Understanding Cancer Aneuploidy

  Cancer Cell · 2018 · 10.1016/j.ccell.2018.03.007

• Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

  Cell Reports · 2018 · 10.1016/j.celrep.2018.03.086

• Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

  Cancer Cell · 2018 · 10.1016/j.ccell.2018.07.001

• An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

  Cell · 2018 · 10.1016/j.cell.2018.02.052

• Oncogenic Signaling Pathways in The Cancer Genome Atlas

  Cell · 2018 · 10.1016/j.cell.2018.03.035

• Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

  Cell · 2018 · 10.1016/j.cell.2018.03.022

• Comprehensive Characterization of Cancer Driver Genes and Mutations

  Cell · 2018 · 10.1016/j.cell.2018.02.060

• Analysis of the Prevalence of Microsatellite Instability in Prostate Cancer and Response to Immune Checkpoint Blockade

  JAMA Oncology · 2018 · 10.1001/jamaoncol.2018.5801

• Prospective Genotyping of Hepatocellular Carcinoma: Clinical Implications of Next-Generation Sequencing for Matching Patients to Targeted and Immune Therapies

  Clinical Cancer Research · 2018 · 10.1158/1078-0432.ccr-18-2293

• Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

  Cell Systems · 2018 · 10.1016/j.cels.2018.03.002

• Pathogenic Germline Variants in 10,389 Adult Cancers

  Cell · 2018 · 10.1016/j.cell.2018.03.039

• The long tail of oncogenic drivers in prostate cancer

  Nature Genetics · 2018 · 10.1038/s41588-018-0078-z

• Driver Fusions and Their Implications in the Development and Treatment of Human Cancers

  Cell Reports · 2018 · 10.1016/j.celrep.2018.03.050

• Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas

  Cancer Cell · 2018 · 10.1016/j.ccell.2018.03.010

• Integrative Molecular Characterization of Malignant Pleural Mesothelioma

  Cancer Discovery · 2018 · 10.1158/2159-8290.cd-18-0804

• Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer

  Cell Reports · 2018 · 10.1016/j.celrep.2018.10.001

• lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer

  Cancer Cell · 2018 · 10.1016/j.ccell.2018.03.006

• Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types

  Cell Reports · 2018 · 10.1016/j.celrep.2018.01.088

• Genome doubling shapes the evolution and prognosis of advanced cancers

  Nature Genetics · 2018 · 10.1038/s41588-018-0165-1

• Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making

  JCO Precision Oncology · 2017 · 10.1200/po.17.00029

• The Molecular Taxonomy of Primary Prostate Cancer

  Cell · 2015 · 10.1016/j.cell.2015.10.025

Current projects

No projects listed.