Steven A. Lubitz

Research interests

Publications

• European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the State of Genetic Testing for Cardiac Diseases

  Heart Rhythm · 2022 · https://doi.org/10.1016/j.hrthm.2022.03.1225

• European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the state of genetic testing for cardiac diseases

  EP Europace · 2022 · https://doi.org/10.1093/europace/euac030

• Detection of Atrial Fibrillation in a Large Population Using Wearable Devices: The Fitbit Heart Study

  Circulation · 2022 · 10.1161/circulationaha.122.060291

• ECG-Based Deep Learning and Clinical Risk Factors to Predict Atrial Fibrillation

  Circulation · 2021 · 10.1161/circulationaha.121.057480

• Inherited causes of clonal haematopoiesis in 97,691 whole genomes

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2819-2

• Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals

  Nature Metabolism · 2020 · https://doi.org/10.1038/s42255-020-00287-2

• 2020 APHRS/HRS expert consensus statement on the investigation of decedents with sudden unexplained death and patients with sudden cardiac arrest, and of their families

  Heart Rhythm · 2020 · https://doi.org/10.1016/j.hrthm.2020.10.010

• Sudden Cardiac Arrest Survivorship: A Scientific Statement From the American Heart Association

  Circulation · 2020 · 10.1161/cir.0000000000000747

• Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy

  Nature Communications · 2020 · 10.1038/s41467-020-15823-7

• Recovery of trait heritability from whole genome sequence data

  bioRxiv (Cold Spring Harbor Laboratory) · 2019 · https://doi.org/10.1101/588020

• Predicting Benefit From Evolocumab Therapy in Patients With Atherosclerotic Disease Using a Genetic Risk Score

  Circulation · 2019 · https://doi.org/10.1161/circulationaha.119.043805

• Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

  bioRxiv (Cold Spring Harbor Laboratory) · 2019 · https://doi.org/10.1101/563866

• Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

  PLoS Genetics · 2019 · https://doi.org/10.1371/journal.pgen.1008500

• Frequency of Cardiac Rhythm Abnormalities in a Half Million Adults

  Circulation Arrhythmia and Electrophysiology · 2018 · 10.1161/circep.118.006273

• Lifetime risk of atrial fibrillation according to optimal, borderline, or elevated levels of risk factors: cohort study based on longitudinal data from the Framingham Heart Study

  BMJ · 2018 · 10.1136/bmj.k1453

• Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0183-z

• Genetic Predisposition, Clinical Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation

  Circulation · 2017 · 10.1161/circulationaha.117.031431

• Genetic loci associated with heart rate variability and their effects on cardiac disease risk

  Nature Communications · 2017 · https://doi.org/10.1038/ncomms15805

• Atrial Fibrillation Begets Heart Failure and Vice Versa

  Circulation · 2016 · https://doi.org/10.1161/circulationaha.115.018614

• Oral Anticoagulant Therapy Prescription in Patients With Atrial Fibrillation Across the Spectrum of Stroke Risk

  JAMA Cardiology · 2016 · 10.1001/jamacardio.2015.0374

• Actionable exomic incidental findings in 6503 participants: challenges of variant classification

  Genome Research · 2015 · 10.1101/gr.183483.114

• 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study

  The Lancet · 2015 · https://doi.org/10.1016/s0140-6736(14)61774-8

• Simple Risk Model Predicts Incidence of Atrial Fibrillation in a Racially and Geographically Diverse Population: the CHARGE‐AF Consortium

  Journal of the American Heart Association · 2013 · 10.1161/jaha.112.000102

• Meta-analysis identifies six new susceptibility loci for atrial fibrillation

  Nature Genetics · 2012 · 10.1038/ng.2261

• Common variants in KCNN3 are associated with lone atrial fibrillation

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.537

• Association Between Familial Atrial Fibrillation and Risk of New-Onset Atrial Fibrillation

  JAMA · 2010 · 10.1001/jama.2010.1690

• Genome-wide association study of PR interval

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.517

• Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry

  Nature Genetics · 2009 · 10.1038/ng.416

• Cardiac Involvement in Patients with Sarcoidosis

  CHEST Journal · 2008 · 10.1378/chest.07-2784

Current projects

No projects listed.