Ditte Demontis

Research interests

Publications

• Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains

  Nature Genetics · 2023 · https://doi.org/10.1038/s41588-022-01285-8

• Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals

  Nature Medicine · 2023 · 10.1038/s41591-023-02653-5

• Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses

  Nature Medicine · 2023 · 10.1038/s41591-023-02352-1

• Mapping genomic loci implicates genes and synaptic biology in schizophrenia

  Nature · 2022 · https://doi.org/10.1038/s41586-022-04434-5

• Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci

  Molecular Psychiatry · 2022 · 10.1038/s41380-022-01709-1

• A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts

  Biological Psychiatry · 2021 · 10.1016/j.biopsych.2021.04.018

• A large-scale genome-wide association study meta-analysis of cannabis use disorder

  The Lancet Psychiatry · 2020 · 10.1016/s2215-0366(20)30339-4

• Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

  Nature Genetics · 2019 · 10.1038/s41588-019-0364-4

• Autism spectrum disorder and attention deficit hyperactivity disorder have a similar burden of rare protein-truncating variants

  Nature Neuroscience · 2019 · 10.1038/s41593-019-0527-8

• Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

  Cell · 2019 · https://doi.org/10.1016/j.cell.2019.11.020

• GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores

  American Journal of Psychiatry · 2019 · 10.1176/appi.ajp.2019.18080957

• Identification of common genetic risk variants for autism spectrum disorder

  Nature Genetics · 2019 · https://doi.org/10.1038/s41588-019-0344-8

• Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0269-7

• Estimation of Genetic Correlation via Linkage Disequilibrium Score Regression and Genomic Restricted Maximum Likelihood

  The American Journal of Human Genetics · 2018 · 10.1016/j.ajhg.2018.03.021

• Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls

  Psychological Medicine · 2018 · 10.1017/s0033291718002039

• Discovery of the first genome-wide significant risk loci for ADHD

  bioRxiv (Cold Spring Harbor Laboratory) · 2017 · 10.1101/145581

• A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder

  Biological Psychiatry · 2017 · 10.1016/j.biopsych.2017.11.026

• A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder

  Biological Psychiatry · 2017 · 10.1016/j.biopsych.2017.11.026

• Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

  The American Journal of Human Genetics · 2015 · 10.1016/j.ajhg.2015.09.001

• Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios

  Nature Communications · 2015 · 10.1038/ncomms6969

• Biological insights from 108 schizophrenia-associated genetic loci

  Nature · 2014 · 10.1038/nature13595

• Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

  The American Journal of Human Genetics · 2014 · 10.1016/j.ajhg.2014.10.004

• Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci

  Molecular Psychiatry · 2013 · 10.1038/mp.2013.2

• Common variants at VRK2 and TCF4 conferring risk of schizophrenia

  Human Molecular Genetics · 2011 · 10.1093/hmg/ddr325

• CACNA1C (rs1006737) is associated with schizophrenia

  Molecular Psychiatry · 2010 · 10.1038/mp.2009.69

Current projects

No projects listed.