Melina Claussnitzer

Research interests

Publications

• Multi-ancestry polygenic mechanisms of type 2 diabetes

  Nature Medicine · 2024 · https://doi.org/10.1038/s41591-024-02865-3

• The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits

  Cell Metabolism · 2023 · https://doi.org/10.1016/j.cmet.2023.03.001

• Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots

  Nature Communications · 2022 · https://doi.org/10.1038/s41467-022-30931-2

• A single-cell atlas of human and mouse white adipose tissue

  Nature · 2022 · https://doi.org/10.1038/s41586-022-04518-2

• Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5

  Science · 2021 · https://doi.org/10.1126/science.abf1008

• A brief history of human disease genetics

  Nature · 2020 · https://doi.org/10.1038/s41586-019-1879-7

• High-resolution genome-wide functional dissection of transcriptional regulatory regions and nucleotides in human

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-07746-1

• Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

  Nature Communications · 2017 · https://doi.org/10.1038/s41467-017-00031-7

• FTO Obesity Variant Circuitry and Adipocyte Browning in Humans

  New England Journal of Medicine · 2015 · https://doi.org/10.1056/nejmoa1502214

• Integrative analysis of 111 reference human epigenomes

  Nature · 2015 · https://doi.org/10.1038/nature14248

• Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture

  Nature · 2015 · https://doi.org/10.1038/nature14878

• Leveraging Cross-Species Transcription Factor Binding Site Patterns: From Diabetes Risk Loci to Disease Mechanisms

  Cell · 2014 · https://doi.org/10.1016/j.cell.2013.10.058

Current projects

No projects listed.