Patrick T. Ellinor

Research interests

Publications

• A genomic mutational constraint map using variation in 76,156 human genomes

  Nature · 2023 · https://doi.org/10.1038/s41586-023-06045-0

• Transfer learning enables predictions in network biology

  Nature · 2023 · https://doi.org/10.1038/s41586-023-06139-9

• Unsupervised removal of systematic background noise from droplet-based single-cell experiments using CellBender

  Nature Methods · 2023 · https://doi.org/10.1038/s41592-023-01943-7

• Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

  Nature Genetics · 2022 · https://doi.org/10.1038/s41588-022-01233-6

• Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03205-y

• COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets

  Nature · 2021 · 10.1038/s41586-021-03570-8

• Inherited causes of clonal haematopoiesis in 97,691 whole genomes

  Nature · 2020 · 10.1038/s41586-020-2819-2

• The mutational constraint spectrum quantified from variation in 141,456 humans

  Nature · 2020 · 10.1038/s41586-020-2308-7

• 2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society in Collaboration With the Society of Thoracic Surgeons

  Circulation · 2019 · 10.1161/cir.0000000000000665

• 2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation

  Journal of the American College of Cardiology · 2019 · 10.1016/j.jacc.2019.01.011

• Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

  Nature Genetics · 2018 · 10.1038/s41588-018-0183-z

• 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation: Executive summary

  Journal of Arrhythmia · 2017 · 10.1016/j.joa.2017.08.001

• Macrophages Facilitate Electrical Conduction in the Heart

  Cell · 2017 · 10.1016/j.cell.2017.03.050

• Association analyses based on false discovery rate implicate new loci for coronary artery disease

  Nature Genetics · 2017 · 10.1038/ng.3913

• 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation

  Heart Rhythm · 2017 · 10.1016/j.hrthm.2017.05.012

• 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation

  EP Europace · 2017 · 10.1093/europace/eux274

• Rare and low-frequency coding variants alter human adult height

  Nature · 2017 · 10.1038/nature21039

• Atrial Fibrillation Begets Heart Failure and Vice Versa

  Circulation · 2016 · 10.1161/circulationaha.115.018614

• 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study

  The Lancet · 2015 · 10.1016/s0140-6736(14)61774-8

• 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: Executive Summary

  Circulation · 2014 · 10.1161/cir.0000000000000040

• 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation

  Circulation · 2014 · 10.1161/cir.0000000000000041

• 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation

  Journal of the American College of Cardiology · 2014 · 10.1016/j.jacc.2014.03.022

• Simple Risk Model Predicts Incidence of Atrial Fibrillation in a Racially and Geographically Diverse Population: the CHARGE‐AF Consortium

  Journal of the American Heart Association · 2013 · 10.1161/jaha.112.000102

• Meta-analysis identifies six new susceptibility loci for atrial fibrillation

  Nature Genetics · 2012 · 10.1038/ng.2261

• HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the Channelopathies and Cardiomyopathies

  Heart Rhythm · 2011 · 10.1016/j.hrthm.2011.05.020

• HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the Channelopathies and Cardiomyopathies

  EP Europace · 2011 · 10.1093/europace/eur245

• Development of a risk score for atrial fibrillation (Framingham Heart Study): a community-based cohort study

  The Lancet · 2009 · 10.1016/s0140-6736(09)60443-8

• Variants conferring risk of atrial fibrillation on chromosome 4q25

  Nature · 2007 · 10.1038/nature06007

• Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy

  Nature Genetics · 2004 · 10.1038/ng1461

Current projects

No projects listed.