Aviv Regev

Research interests

Publications

• A single-cell atlas of human and mouse white adipose tissue

  Nature · 2022 · https://doi.org/10.1038/s41586-022-04518-2

• A multimodal cell census and atlas of the mammalian primary motor cortex

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03950-0

• Spatially organized multicellular immune hubs in human colorectal cancer

  Cell · 2021 · https://doi.org/10.1016/j.cell.2021.08.003

• Comparative cellular analysis of motor cortex in human, marmoset and mouse

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03465-8

• SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

  Cell · 2020 · https://doi.org/10.1016/j.cell.2020.04.035

• An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma

  Cell · 2019 · 10.1016/j.cell.2019.06.024

• Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis

  Cell · 2019 · 10.1016/j.cell.2019.06.029

• Single-cell transcriptomics to explore the immune system in health and disease

  Science · 2017 · 10.1126/science.aan6828

• Nucleic acid detection with CRISPR-Cas13a/C2c2

  Science · 2017 · 10.1126/science.aam9321

• Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer

  Cell · 2017 · 10.1016/j.cell.2017.10.044

• Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

  Science · 2017 · 10.1126/science.aah4573

• RNA targeting with CRISPR–Cas13

  Nature · 2017 · 10.1038/nature24049

• A single-cell survey of the small intestinal epithelium

  Nature · 2017 · 10.1038/nature24489

• The Human Cell Atlas

  Zurich Open Repository and Archive (University of Zurich) · 2017 · 10.5167/uzh-162597

• Massively parallel single-nucleus RNA-seq with DroNc-seq

  Nature Methods · 2017 · 10.1038/nmeth.4407

• The Human Cell Atlas: from vision to reality

  Nature · 2017 · 10.1038/550451a

• C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

  Science · 2016 · 10.1126/science.aaf5573

• Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

  Science · 2016 · https://doi.org/10.1126/science.aad0501

• Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens

  Cell · 2016 · 10.1016/j.cell.2016.11.038

• Spatial reconstruction of single-cell gene expression data

  Nature Biotechnology · 2015 · https://doi.org/10.1038/nbt.3192

• Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

  Cell · 2015 · 10.1016/j.cell.2015.09.038

• Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells

  Genome Research · 2015 · 10.1101/gr.192237.115

• Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

  Cell · 2015 · https://doi.org/10.1016/j.cell.2015.05.002

• CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling

  Cell · 2014 · 10.1016/j.cell.2014.09.014

• De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis

  Nature Protocols · 2013 · https://doi.org/10.1038/nprot.2013.084

• Full-length transcriptome assembly from RNA-Seq data without a reference genome

  Nature Biotechnology · 2011 · https://doi.org/10.1038/nbt.1883

• lincRNAs act in the circuitry controlling pluripotency and differentiation

  Nature · 2011 · 10.1038/nature10398

• Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis

  Cell · 2011 · 10.1016/j.cell.2011.01.004

• Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

  Genes & Development · 2011 · 10.1101/gad.17446611

• Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium

  Nature · 2010 · 10.1038/nature08850

• A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response

  Cell · 2010 · 10.1016/j.cell.2010.06.040

• Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

  Nature · 2009 · 10.1038/nature07672

• SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

  Nature Genetics · 2009 · 10.1038/ng.465

• Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

  Proceedings of the National Academy of Sciences · 2009 · 10.1073/pnas.0904715106

• An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

  Nature Genetics · 2008 · 10.1038/ng.127

• Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data

  Nature Genetics · 2003 · 10.1038/ng1165

Current projects

No projects listed.