Giulio Genovese

Research interests

Publications

• Mapping genomic loci implicates genes and synaptic biology in schizophrenia

  Nature · 2022 · https://doi.org/10.1038/s41586-022-04434-5

• Rare coding variants in ten genes confer substantial risk for schizophrenia

  Nature · 2022 · https://doi.org/10.1038/s41586-022-04556-w

• Monogenic and polygenic inheritance become instruments for clonal selection

  Nature · 2020 · 10.1038/s41586-020-2430-6

• Genetic predisposition to mosaic Y chromosome loss in blood

  Nature · 2019 · 10.1038/s41586-019-1765-3

• Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0081-4

• Chromosomal instability drives metastasis through a cytosolic DNA response

  Nature · 2018 · https://doi.org/10.1038/nature25432

• Increased neutrophil extracellular trap formation promotes thrombosis in myeloproliferative neoplasms

  Science Translational Medicine · 2018 · https://doi.org/10.1126/scitranslmed.aan8292

• Insights into clonal haematopoiesis from 8,342 mosaic chromosomal alterations

  Nature · 2018 · 10.1038/s41586-018-0321-x

• The Genetic Landscape of Diamond-Blackfan Anemia

  The American Journal of Human Genetics · 2018 · 10.1016/j.ajhg.2018.10.027

• Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations

  Nature · 2017 · 10.1038/nature22312

• Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia

  Nature Neuroscience · 2016 · 10.1038/nn.4402

• Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

  Nature Genetics · 2016 · 10.1038/ng.3725

• Schizophrenia risk from complex variation of complement component 4

  Nature · 2016 · 10.1038/nature16549

• Large multiallelic copy number variations in humans

  Nature Genetics · 2015 · 10.1038/ng.3200

• Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

  The American Journal of Human Genetics · 2015 · 10.1016/j.ajhg.2015.09.001

• Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence

  New England Journal of Medicine · 2014 · 10.1056/nejmoa1409405

• A polygenic burden of rare disruptive mutations in schizophrenia

  Nature · 2014 · 10.1038/nature12975

• Integrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel

  Nature Communications · 2014 · 10.1038/ncomms4934

• Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

  The American Journal of Human Genetics · 2014 · 10.1016/j.ajhg.2014.10.004

• Biological insights from 108 schizophrenia-associated genetic loci

  Nature · 2014 · 10.1038/nature13595

• APOL1 Genetic Variants in Focal Segmental Glomerulosclerosis and HIV-Associated Nephropathy

  Journal of the American Society of Nephrology · 2011 · 10.1681/asn.2011040388

• Population-Based Risk Assessment of APOL1 on Renal Disease

  Journal of the American Society of Nephrology · 2011 · 10.1681/asn.2011050519

• The Apolipoprotein L1 (APOL1) Gene and Nondiabetic Nephropathy in African Americans

  Journal of the American Society of Nephrology · 2010 · 10.1681/asn.2010070730

• Association of Trypanolytic ApoL1 Variants with Kidney Disease in African Americans

  Science · 2010 · 10.1126/science.1193032

• Deviant Kinetochore Microtubule Dynamics Underlie Chromosomal Instability

  Current Biology · 2009 · 10.1016/j.cub.2009.09.055

Current projects

No projects listed.