Matthew Meyerson

Research interests

Publications

• Discovering the anticancer potential of non-oncology drugs by systematic viability profiling

  Nature Cancer · 2020 · https://doi.org/10.1038/s43018-019-0018-6

• Mutational signature in colorectal cancer caused by genotoxic pks+ E. coli

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2080-8

• Commensal Microbiota Promote Lung Cancer Development via γδ T Cells

  Cell · 2019 · https://doi.org/10.1016/j.cell.2018.12.040

• Oncogenic Signaling Pathways in The Cancer Genome Atlas

  Cell · 2018 · https://doi.org/10.1016/j.cell.2018.03.035

• Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes

  Nature Medicine · 2018 · https://doi.org/10.1038/s41591-018-0016-8

• Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer

  Science · 2017 · 10.1126/science.aal5240

• Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

  Cell · 2017 · 10.1016/j.cell.2017.09.007

• Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

  Cell · 2017 · 10.1016/j.cell.2017.05.046

• Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

  Cancer Cell · 2017 · 10.1016/j.ccell.2017.07.007

• Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma

  Cancer Cell · 2016 · 10.1016/j.ccell.2016.04.002

• Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma

  Cancer Cell · 2016 · 10.1016/j.ccell.2016.04.002

• Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

  Nature Genetics · 2016 · 10.1038/ng.3564

• Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

  Cell · 2016 · 10.1016/j.cell.2015.12.028

• Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

  Cell · 2015 · 10.1016/j.cell.2015.03.053

• Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets

  Cancer Discovery · 2015 · 10.1158/2159-8290.cd-15-0369

• Comprehensive molecular characterization of urothelial bladder carcinoma

  Nature · 2014 · 10.1038/nature12965

• Comprehensive molecular characterization of gastric adenocarcinoma

  Nature · 2014 · 10.1038/nature13480

• The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma

  Cancer Cell · 2014 · 10.1016/j.ccr.2014.07.014

• Discovery and saturation analysis of cancer genes across 21 tumour types

  Nature · 2014 · 10.1038/nature12912

• The genetic landscape of high-risk neuroblastoma

  Nature Genetics · 2013 · 10.1038/ng.2529

• Signatures of mutational processes in human cancer

  Nature · 2013 · https://doi.org/10.1038/nature12477

• Mutational heterogeneity in cancer and the search for new cancer-associated genes

  Nature · 2013 · 10.1038/nature12213

• Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

  Cell Host & Microbe · 2013 · 10.1016/j.chom.2013.07.007

• Pan-cancer patterns of somatic copy number alteration

  Nature Genetics · 2013 · 10.1038/ng.2760

• Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia

  Cell · 2013 · 10.1016/j.cell.2013.01.019

• Punctuated Evolution of Prostate Cancer Genomes

  Cell · 2013 · 10.1016/j.cell.2013.03.021

• Absolute quantification of somatic DNA alterations in human cancer

  Nature Biotechnology · 2012 · 10.1038/nbt.2203

• The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

  Nature · 2012 · https://doi.org/10.1038/nature11003

• Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

  Journal of Clinical Investigation · 2012 · 10.1172/jci65833

• A Landscape of Driver Mutations in Melanoma

  Cell · 2012 · 10.1016/j.cell.2012.06.024

• Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

  Nature · 2012 · 10.1038/nature11329

• Dissecting the genomic complexity underlying medulloblastoma

  Nature · 2012 · 10.1038/nature11284

• Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

  Cell · 2012 · 10.1016/j.cell.2012.08.029

• Genomic analysis identifies association of Fusobacterium with colorectal carcinoma

  Genome Research · 2011 · 10.1101/gr.126573.111

• The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

  Science · 2011 · 10.1126/science.1208130

• Initial genome sequencing and analysis of multiple myeloma

  Nature · 2011 · 10.1038/nature09837

• The genomic complexity of primary human prostate cancer

  Nature · 2011 · 10.1038/nature09744

• Integrated genomic analyses of ovarian carcinoma

  Nature · 2011 · https://doi.org/10.1038/nature10166

• Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

  Cancer Cell · 2010 · 10.1016/j.ccr.2009.12.020

• The landscape of somatic copy-number alteration across human cancers

  Nature · 2010 · 10.1038/nature08822

• Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

  Nature · 2009 · 10.1038/nature08460

• SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

  Nature Genetics · 2009 · 10.1038/ng.465

• Comprehensive genomic characterization defines human glioblastoma genes and core pathways

  Nature · 2008 · https://doi.org/10.1038/nature07385

• Somatic mutations affect key pathways in lung adenocarcinoma

  Nature · 2008 · 10.1038/nature07423

• High-throughput oncogene mutation profiling in human cancer

  Nature Genetics · 2007 · 10.1038/ng1975

• Characterizing the cancer genome in lung adenocarcinoma

  Nature · 2007 · 10.1038/nature06358

• Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

  Proceedings of the National Academy of Sciences · 2007 · 10.1073/pnas.0710052104

• Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

  Cancer Cell · 2005 · 10.1016/j.ccr.2005.03.023

• EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib

  New England Journal of Medicine · 2005 · 10.1056/nejmoa044238

• EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy

  Science · 2004 · https://doi.org/10.1126/science.1099314

• Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

  Proceedings of the National Academy of Sciences · 2001 · 10.1073/pnas.191502998

Current projects

No projects listed.