Michael S. Lawrence
Researcher Next ID · RN-019636
Researcher · Biochemistry, Genetics and Molecular Biology
Cambridge, United States
- Works count
- 744
- Citation count
- 215,034
- H-index
- 150
- i10-index
- 251
Research interests
Publications
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
Nature · 2020 · https://doi.org/10.1038/s41586-020-1965-x
The repertoire of mutational signatures in human cancer
Nature · 2020 · https://doi.org/10.1038/s41586-020-1943-3
Next-generation characterization of the Cancer Cell Line Encyclopedia
Nature · 2019 · https://doi.org/10.1038/s41586-019-1186-3
The Immune Landscape of Cancer
Immunity · 2018 · https://doi.org/10.1016/j.immuni.2018.03.023
Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines
Cell Systems · 2018 · https://doi.org/10.1016/j.cels.2018.03.002
Comprehensive Characterization of Cancer Driver Genes and Mutations
Cell · 2018 · https://doi.org/10.1016/j.cell.2018.02.060
An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics
Cell · 2018 · 10.1016/j.cell.2018.02.052
Oncogenic Signaling Pathways in The Cancer Genome Atlas
Cell · 2018 · 10.1016/j.cell.2018.03.035
Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer
Cell · 2018 · 10.1016/j.cell.2018.03.022
Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer
Cell · 2018 · 10.1016/j.cell.2018.03.022
Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation
Cell · 2018 · 10.1016/j.cell.2018.03.034
Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas
Cell Reports · 2018 · 10.1016/j.celrep.2018.03.076
Genomic and Functional Approaches to Understanding Cancer Aneuploidy
Cancer Cell · 2018 · 10.1016/j.ccell.2018.03.007
Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images
Cell Reports · 2018 · 10.1016/j.celrep.2018.03.086
Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients
Cancer Cell · 2018 · 10.1016/j.ccell.2018.07.001
Pathogenic Germline Variants in 10,389 Adult Cancers
Cell · 2018 · 10.1016/j.cell.2018.03.039
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma
Cell Reports · 2018 · 10.1016/j.celrep.2018.03.075
Driver Fusions and Their Implications in the Development and Treatment of Human Cancers
Cell Reports · 2018 · 10.1016/j.celrep.2018.03.050
A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers
Cancer Cell · 2018 · 10.1016/j.ccell.2018.03.014
Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas
Cancer Cell · 2018 · 10.1016/j.ccell.2018.03.010
Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer
Cell Reports · 2018 · 10.1016/j.celrep.2018.10.001
lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer
Cancer Cell · 2018 · 10.1016/j.ccell.2018.03.006
Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types
Cell Reports · 2018 · 10.1016/j.celrep.2018.01.088
Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma
Cancer Cell · 2017 · 10.1016/j.ccell.2017.07.003
Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma
Cell · 2017 · 10.1016/j.cell.2017.05.046
Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma
Cancer Cell · 2017 · 10.1016/j.ccell.2017.07.007
Integrated genomic and molecular characterization of cervical cancer
Nature · 2017 · 10.1038/nature21386
Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets
Cancer Discovery · 2015 · 10.1158/2159-8290.cd-15-0369
Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer
Cell · 2015 · 10.1016/j.cell.2015.09.033
Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients
Cell · 2015 · 10.1016/j.cell.2015.03.053
Comprehensive molecular characterization of urothelial bladder carcinoma
Nature · 2014 · 10.1038/nature12965
Discovery and saturation analysis of cancer genes across 21 tumour types
Nature · 2014 · 10.1038/nature12912
Comprehensive molecular characterization of gastric adenocarcinoma
Nature · 2014 · https://doi.org/10.1038/nature13480
Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes
Nature Genetics · 2014 · 10.1038/ng.3168
Comprehensive molecular profiling of lung adenocarcinoma
Nature · 2014 · 10.1038/nature13385
Punctuated Evolution of Prostate Cancer Genomes
Cell · 2013 · 10.1016/j.cell.2013.03.021
Pan-cancer patterns of somatic copy number alteration
Nature Genetics · 2013 · 10.1038/ng.2760
Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia
Cell · 2013 · 10.1016/j.cell.2013.01.019
Comprehensive molecular characterization of clear cell renal cell carcinoma
Nature · 2013 · 10.1038/nature12222
Mutational heterogeneity in cancer and the search for new cancer-associated genes
Nature · 2013 · 10.1038/nature12213
The genetic landscape of high-risk neuroblastoma
Nature Genetics · 2013 · 10.1038/ng.2529
Comprehensive genomic characterization of squamous cell lung cancers
Nature · 2012 · 10.1038/nature11404
Prognostically relevant gene signatures of high-grade serous ovarian carcinoma
Journal of Clinical Investigation · 2012 · 10.1172/jci65833
Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing
Cell · 2012 · 10.1016/j.cell.2012.08.029
Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations
Nature · 2012 · 10.1038/nature11329
A Landscape of Driver Mutations in Melanoma
Cell · 2012 · 10.1016/j.cell.2012.06.024
Integrated genomic analyses of ovarian carcinoma
Nature · 2011 · https://doi.org/10.1038/nature10166
The Mutational Landscape of Head and Neck Squamous Cell Carcinoma
Science · 2011 · 10.1126/science.1208130
The genomic complexity of primary human prostate cancer
Nature · 2011 · 10.1038/nature09744
Initial genome sequencing and analysis of multiple myeloma
Nature · 2011 · 10.1038/nature09837
The landscape of somatic copy-number alteration across human cancers
Nature · 2010 · 10.1038/nature08822
Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
Cancer Cell · 2010 · https://doi.org/10.1016/j.ccr.2009.12.020
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Nature · 2008 · https://doi.org/10.1038/nature07385
Somatic mutations affect key pathways in lung adenocarcinoma
Nature · 2008 · 10.1038/nature07423
Current projects
No projects listed.