Zhengming Chen

Research interests

Publications

• Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference

  Nature Genetics · 2024 · https://doi.org/10.1038/s41588-023-01596-4

• Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

  Nature · 2024 · https://doi.org/10.1038/s41586-024-07019-6

• Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

  Nature Genetics · 2023 · https://doi.org/10.1038/s41588-023-01314-0

• Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

  Nature Genetics · 2022 · https://doi.org/10.1038/s41588-022-01058-3

• Stroke genetics informs drug discovery and risk prediction across ancestries

  Nature · 2022 · https://doi.org/10.1038/s41586-022-05165-3

• Lifestyle, cardiometabolic disease, and multimorbidity in a prospective Chinese study

  European Heart Journal · 2021 · https://doi.org/10.1093/eurheartj/ehab413

• Frailty index and all-cause and cause-specific mortality in Chinese adults: a prospective cohort study

  The Lancet Public Health · 2020 · https://doi.org/10.1016/s2468-2667(20)30113-4

• Identification of type 2 diabetes loci in 433,540 East Asian individuals

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2263-3

• Association of Depression With All-Cause and Cardiovascular Disease Mortality Among Adults in China

  JAMA Network Open · 2020 · https://doi.org/10.1001/jamanetworkopen.2019.21043

• New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

  Nature Genetics · 2019 · https://doi.org/10.1038/s41588-018-0321-7

• Stroke in China: advances and challenges in epidemiology, prevention, and management

  The Lancet Neurology · 2019 · https://doi.org/10.1016/s1474-4422(18)30500-3

• Causal associations of blood lipids with risk of ischemic stroke and intracerebral hemorrhage in Chinese adults

  Nature Medicine · 2019 · https://doi.org/10.1038/s41591-019-0366-x

• Conventional and genetic evidence on alcohol and vascular disease aetiology: a prospective study of 500 000 men and women in China

  The Lancet · 2019 · https://doi.org/10.1016/s0140-6736(18)31772-0

• Prevalence, risk factors, and management of asthma in China: a national cross-sectional study

  The Lancet · 2019 · 10.1016/s0140-6736(19)31147-x

• Association of Solid Fuel Use With Risk of Cardiovascular and All-Cause Mortality in Rural China

  JAMA · 2018 · https://doi.org/10.1001/jama.2018.2151

• Lipids, Lipoproteins, and Metabolites and Risk of Myocardial Infarction and Stroke

  Journal of the American College of Cardiology · 2018 · https://doi.org/10.1016/j.jacc.2017.12.006

• Adherence to Healthy Lifestyle and Cardiovascular Diseases in the Chinese Population

  Journal of the American College of Cardiology · 2017 · https://doi.org/10.1016/j.jacc.2016.11.076

• Adherence to Healthy Lifestyle and Cardiovascular Diseases in the Chinese Population

  Journal of the American College of Cardiology · 2017 · https://doi.org/10.1016/j.jacc.2016.11.076

• Adherence to Healthy Lifestyle and Cardiovascular Diseases in the Chinese Population

  Journal of the American College of Cardiology · 2017 · https://doi.org/10.1016/j.jacc.2016.11.076

• Association Between Diabetes and Cause-Specific Mortality in Rural and Urban Areas of China

  JAMA · 2017 · https://doi.org/10.1001/jama.2016.19720

• The Burden of Hypertension and Associated Risk for Cardiovascular Mortality in China

  JAMA Internal Medicine · 2016 · https://doi.org/10.1001/jamainternmed.2016.0190

• Fresh Fruit Consumption and Major Cardiovascular Disease in China

  New England Journal of Medicine · 2016 · https://doi.org/10.1056/nejmoa1501451

• Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents

  The Lancet · 2016 · 10.1016/s0140-6736(16)30175-1

• Contrasting male and female trends in tobacco-attributed mortality in China: evidence from successive nationwide prospective cohort studies

  The Lancet · 2015 · https://doi.org/10.1016/s0140-6736(15)00340-2

• Respiratory risks from household air pollution in low and middle income countries

  The Lancet Respiratory Medicine · 2014 · 10.1016/s2213-2600(14)70168-7

• Physical activity and sedentary leisure time and their associations with BMI, waist circumference, and percentage body fat in 0.5 million adults: the China Kadoorie Biobank study

  American Journal of Clinical Nutrition · 2013 · https://doi.org/10.3945/ajcn.112.046854

• The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial

  The Lancet · 2011 · 10.1016/s0140-6736(11)60739-3

• Cohort Profile: The Kadoorie Study of Chronic Disease in China (KSCDC)

  International Journal of Epidemiology · 2005 · https://doi.org/10.1093/ije/dyi174

Current projects

No projects listed.