Stephan Ripke

Research interests

Publications

• Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

  Nature Genetics · 2021 · https://doi.org/10.1038/s41588-021-00973-1

• Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

  Nature Genetics · 2019 · https://doi.org/10.1038/s41588-019-0439-2

• Identification of common genetic risk variants for autism spectrum disorder

  Nature Genetics · 2019 · 10.1038/s41588-019-0344-8

• Genome-wide association study identifies 30 loci associated with bipolar disorder

  Nature Genetics · 2019 · https://doi.org/10.1038/s41588-019-0397-8

• Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

  Nature Genetics · 2019 · https://doi.org/10.1038/s41588-018-0311-9

• Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

  Nature Neuroscience · 2019 · https://doi.org/10.1038/s41593-018-0326-7

• Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

  Nature Genetics · 2018 · 10.1038/s41588-018-0269-7

• Analysis of shared heritability in common disorders of the brain

  Science · 2018 · 10.1126/science.aap8757

• Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

  Science · 2018 · 10.1126/science.aad6469

• Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

  Cell · 2018 · 10.1016/j.cell.2018.05.046

• Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

  Nature Genetics · 2018 · 10.1038/s41588-018-0059-2

• Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

  Nature Genetics · 2018 · 10.1038/s41588-018-0090-3

• Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

  Nature Genetics · 2016 · 10.1038/ng.3725

• LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

  Nature Genetics · 2015 · 10.1038/ng.3211

• Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

  The American Journal of Human Genetics · 2015 · 10.1016/j.ajhg.2015.09.001

• Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

  Nature Genetics · 2015 · 10.1038/ng.3359

• Partitioning heritability by functional annotation using genome-wide association summary statistics

  Nature Genetics · 2015 · 10.1038/ng.3404

• Most genetic risk for autism resides with common variation

  Nature Genetics · 2014 · 10.1038/ng.3039

• Defining the role of common variation in the genomic and biological architecture of adult human height

  Nature Genetics · 2014 · 10.1038/ng.3097

• Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

  The American Journal of Human Genetics · 2014 · 10.1016/j.ajhg.2014.10.004

• Partitioning Heritability of Regulatory and Cell-Type-Specific Variants across 11 Common Diseases

  The American Journal of Human Genetics · 2014 · 10.1016/j.ajhg.2014.10.004

• Biological insights from 108 schizophrenia-associated genetic loci

  Nature · 2014 · 10.1038/nature13595

• Genome-wide association analysis identifies 13 new risk loci for schizophrenia

  Nature Genetics · 2013 · 10.1038/ng.2742

• Seven new loci associated with age-related macular degeneration

  Nature Genetics · 2013 · 10.1038/ng.2578

• Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

  Nature · 2012 · 10.1038/nature11582

• A mega-analysis of genome-wide association studies for major depressive disorder

  Molecular Psychiatry · 2012 · 10.1038/mp.2012.21

• Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

  Nature Genetics · 2011 · 10.1038/ng.943

• Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

  Nature Genetics · 2011 · 10.1038/ng.952

• GenABEL: an R library for genome-wide association analysis

  Bioinformatics · 2007 · 10.1093/bioinformatics/btm108

Current projects

No projects listed.