Pradeep Natarajan

Research interests

Publications

• TP53-mediated clonal hematopoiesis confers increased risk for incident atherosclerotic disease

  Nature Cardiovascular Research · 2023 · https://doi.org/10.1038/s44161-022-00206-6

• Prediction of Risk for Myeloid Malignancy in Clonal Hematopoiesis

  NEJM Evidence · 2023 · https://doi.org/10.1056/evidoa2200310

• Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement

  European Heart Journal · 2022 · https://doi.org/10.1093/eurheartj/ehac361

• Large-scale genome-wide association study of coronary artery disease in genetically diverse populations

  Nature Medicine · 2022 · https://doi.org/10.1038/s41591-022-01891-3

• Development of a clinical polygenic risk score assay and reporting workflow

  Nature Medicine · 2022 · https://doi.org/10.1038/s41591-022-01767-6

• Association of Clonal Hematopoiesis With Incident Heart Failure

  Journal of the American College of Cardiology · 2021 · https://doi.org/10.1016/j.jacc.2021.04.085

• Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program

  Circulation · 2020 · https://doi.org/10.1161/circulationaha.120.047544

• Transcriptomic signatures across human tissues identify functional rare genetic variation

  Science · 2020 · https://doi.org/10.1126/science.aaz5900

• Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0222-9

• Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0183-z

• Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-05747-8

• Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease

  New England Journal of Medicine · 2017 · https://doi.org/10.1056/nejmoa1701719

• ANGPTL3 Deficiency and Protection Against Coronary Artery Disease

  Journal of the American College of Cardiology · 2017 · https://doi.org/10.1016/j.jacc.2017.02.030

• Human knockouts and phenotypic analysis in a cohort with a high rate of consanguinity

  Nature · 2017 · https://doi.org/10.1038/nature22034

• Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

  New England Journal of Medicine · 2016 · https://doi.org/10.1056/nejmoa1605086

• Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia

  Journal of the American College of Cardiology · 2016 · 10.1016/j.jacc.2016.03.520

• Analysis of protein-coding genetic variation in 60,706 humans

  Nature · 2016 · 10.1038/nature19057

Current projects

No projects listed.