Amalia Gastaldelli

Research interests

Publications

• Metabolic syndrome

  Nature Reviews Disease Primers · 2024 · https://doi.org/10.1038/s41572-024-00563-5

• EASL–EASD–EASO Clinical Practice Guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD)

  Journal of Hepatology · 2024 · https://doi.org/10.1016/j.jhep.2024.04.031

• Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial

  The Lancet Diabetes & Endocrinology · 2022 · https://doi.org/10.1016/s2213-8587(22)00070-5

• Why does obesity cause diabetes?

  Cell Metabolism · 2022 · https://doi.org/10.1016/j.cmet.2021.12.012

• Metabolomics and lipidomics in NAFLD: biomarkers and non-invasive diagnostic tests

  Nature Reviews Gastroenterology & Hepatology · 2021 · https://doi.org/10.1038/s41575-021-00502-9

• Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: A systematic review and meta-analysis

  Journal of Hepatology · 2021 · https://doi.org/10.1016/j.jhep.2021.04.044

• From NASH to diabetes and from diabetes to NASH: Mechanisms and treatment options

  JHEP Reports · 2019 · https://doi.org/10.1016/j.jhepr.2019.07.002

• Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars

  Diabetes Care · 2018 · https://doi.org/10.2337/dc18-0071

• Altered amino acid concentrations in NAFLD: Impact of obesity and insulin resistance

  Hepatology · 2017 · https://doi.org/10.1002/hep.29465

• Role of Adipose Tissue Insulin Resistance in the Natural History of Type 2 Diabetes: Results From the San Antonio Metabolism Study

  Diabetes · 2017 · https://doi.org/10.2337/db16-1167

• AISF position paper on nonalcoholic fatty liver disease (NAFLD): Updates and future directions

  Digestive and Liver Disease · 2017 · https://doi.org/10.1016/j.dld.2017.01.147

• Pathophysiology of Non Alcoholic Fatty Liver Disease

  International Journal of Molecular Sciences · 2016 · https://doi.org/10.3390/ijms17122082

• The Subtle Balance between Lipolysis and Lipogenesis: A Critical Point in Metabolic Homeostasis

  Nutrients · 2015 · https://doi.org/10.3390/nu7115475

• Non-Alcoholic Fatty Liver Disease (NAFLD) and Its Connection with Insulin Resistance, Dyslipidemia, Atherosclerosis and Coronary Heart Disease

  Nutrients · 2013 · https://doi.org/10.3390/nu5051544

• Glucagon‐like peptide‐1 receptor activation stimulates hepatic lipid oxidation and restores hepatic signalling alteration induced by a high‐fat diet in nonalcoholic steatohepatitis

  Liver International · 2011 · https://doi.org/10.1111/j.1478-3231.2011.02462.x

• Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease

  Hepatology · 2011 · https://doi.org/10.1002/hep.25539

• Fatty liver is associated with insulin resistance, risk of coronary heart disease, and early atherosclerosis in a large European population #

  Hepatology · 2009 · https://doi.org/10.1002/hep.22845

• Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis

  Trends in Molecular Medicine · 2008 · https://doi.org/10.1016/j.molmed.2007.12.003

• Relationship Between Hepatic/Visceral Fat and Hepatic Insulin Resistance in Nondiabetic and Type 2 Diabetic Subjects

  Gastroenterology · 2007 · https://doi.org/10.1053/j.gastro.2007.04.068

• Separate Impact of Obesity and Glucose Tolerance on the Incretin Effect in Normal Subjects and Type 2 Diabetic Patients

  Diabetes · 2007 · https://doi.org/10.2337/db07-1315

• A Placebo-Controlled Trial of Pioglitazone in Subjects with Nonalcoholic Steatohepatitis

  New England Journal of Medicine · 2006 · https://doi.org/10.1056/nejmoa060326

• Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms

  Diabetologia · 2005 · https://doi.org/10.1007/s00125-005-1682-x

• Plasma Adiponectin in Nonalcoholic Fatty Liver Is Related to Hepatic Insulin Resistance and Hepatic Fat Content, Not to Liver Disease Severity

  The Journal of Clinical Endocrinology & Metabolism · 2005 · https://doi.org/10.1210/jc.2004-2240

• β-Cell Function in Subjects Spanning the Range from Normal Glucose Tolerance to Overt Diabetes: A New Analysis

  The Journal of Clinical Endocrinology & Metabolism · 2005 · https://doi.org/10.1210/jc.2004-1133

• Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study

  Diabetologia · 2004 · https://doi.org/10.1007/s00125-003-1263-9

• A Sustained Increase in Plasma Free Fatty Acids Impairs Insulin Secretion in Nondiabetic Subjects Genetically Predisposed to Develop Type 2 Diabetes

  Diabetes · 2003 · https://doi.org/10.2337/diabetes.52.10.2461

• Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration

  American Journal of Physiology-Endocrinology and Metabolism · 1993 · https://doi.org/10.1152/ajpendo.1993.265.3.e380

Current projects

No projects listed.