Paul Ruff

Research interests

Publications

• Barriers to early presentation of breast cancer among women in Soweto, South Africa

  PLoS ONE · 2018 · 10.1371/journal.pone.0192071

• Panitumumab versus cetuximab in patients with chemotherapy-refractory wild-type KRAS exon 2 metastatic colorectal cancer (ASPECCT): a randomised, multicentre, open-label, non-inferiority phase 3 study

  The Lancet Oncology · 2014 · 10.1016/s1470-2045(14)70118-4

• Final results from PRIME: randomized phase III study of panitumumab with FOLFOX4 for first-line treatment of metastatic colorectal cancer

  Annals of Oncology · 2014 · https://doi.org/10.1093/annonc/mdu141

• Aflibercept versus placebo in combination with fluorouracil, leucovorin and irinotecan in the treatment of previously treated metastatic colorectal cancer: Prespecified subgroup analyses from the VELOUR trial

  European Journal of Cancer · 2013 · 10.1016/j.ejca.2013.09.013

• Panitumumab–FOLFOX4 Treatment and RAS Mutations in Colorectal Cancer

  New England Journal of Medicine · 2013 · https://doi.org/10.1056/nejmoa1305275

• Addition of Aflibercept to Fluorouracil, Leucovorin, and Irinotecan Improves Survival in a Phase III Randomized Trial in Patients With Metastatic Colorectal Cancer Previously Treated With an Oxaliplatin-Based Regimen

  Journal of Clinical Oncology · 2012 · https://doi.org/10.1200/jco.2012.42.8201

• Randomized, Phase III Trial of Panitumumab With Infusional Fluorouracil, Leucovorin, and Oxaliplatin (FOLFOX4) Versus FOLFOX4 Alone As First-Line Treatment in Patients With Previously Untreated Metastatic Colorectal Cancer: The PRIME Study

  Journal of Clinical Oncology · 2010 · https://doi.org/10.1200/jco.2009.27.4860

• Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer

  New England Journal of Medicine · 2009 · https://doi.org/10.1056/nejmoa0805019

• Ondansetron Compared with Granisetron in the Prophylaxis of Cisplatin-lnduced Acute Emesis: A Multicentre Double-Blind, Randomised, Parallel-Group Study

  Oncology · 2009 · 10.1159/000227321

• The spectrum of human immunodeficiency virus‐associated cancers in a South African black population: Results from a case–control study, 1995–2004

  International Journal of Cancer · 2008 · 10.1002/ijc.23391

• Correlation of survival with tumor histology, age, and prognostic risk group for previously untreated patients with advanced renal cell carcinoma (adv RCC) receiving temsirolimus (TEMSR) or interferon-alpha (IFN)

  Journal of Clinical Oncology · 2007 · 10.1200/jco.2007.25.18_suppl.5033

• Phase III Randomized Controlled Trial Comparing the Survival of Patients With Unresectable Hepatocellular Carcinoma Treated With Nolatrexed or Doxorubicin

  Journal of Clinical Oncology · 2007 · 10.1200/jco.2006.08.4046

• The relationship between anti-HPV-16 IgG seropositivity and cancer of the cervix, anogenital organs, oral cavity and pharynx, oesophagus and prostate in a black South African population

  Infectious Agents and Cancer · 2007 · 10.1186/1750-9378-2-6

• Risk factors for oesophageal, lung, oral and laryngeal cancers in black South Africans

  British Journal of Cancer · 2002 · 10.1038/sj.bjc.6600338

• The spectrum of HIV-1 related cancers in South Africa

  International Journal of Cancer · 2000 · 10.1002/1097-0215(20001101)88:3<489::aid-ijc25>3.0.co;2-q

• Antibodies against Human Herpesvirus 8 in Black South African Patients with Cancer

  New England Journal of Medicine · 1999 · 10.1056/nejm199906173402403

• In search of a unified definition for mild traumatic brain injury

  Brain Injury · 1999 · 10.1080/026990599120963

• Low Serum Testosterone and a Younger Age Predict for a Poor Outcome in Metastatic Prostate Cancer

  American Journal of Clinical Oncology · 1997 · 10.1097/00000421-199712000-00015

• Molecular identification of a major palmitoylated erythrocyte membrane protein containing the src homology 3 motif.

  Proceedings of the National Academy of Sciences · 1991 · 10.1073/pnas.88.15.6595

• cDNA sequence for human erythrocyte ankyrin.

  Proceedings of the National Academy of Sciences · 1990 · 10.1073/pnas.87.5.1730

• Abnormalities of chromosome 12p 13 and malignant proliferation of eosinophils: a nonrandom association

  British Journal of Haematology · 1987 · 10.1111/j.1365-2141.1987.tb02291.x

Current projects

No projects listed.