Gautam Sethi

Research interests

Publications

• Advances in cancer immunotherapy: historical perspectives, current developments, and future directions

  Molecular Cancer · 2025 · https://doi.org/10.1186/s12943-025-02305-x

• Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

  Journal of Hematology & Oncology · 2024 · https://doi.org/10.1186/s13045-024-01535-8

• PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer

  Molecular Cancer · 2023 · https://doi.org/10.1186/s12943-023-01827-6

• Emerging role of exosomes in cancer progression and tumor microenvironment remodeling

  Journal of Hematology & Oncology · 2022 · https://doi.org/10.1186/s13045-022-01305-4

• Regulation of Nuclear Factor-KappaB (NF-κB) signaling pathway by non-coding RNAs in cancer: Inhibiting or promoting carcinogenesis?

  Cancer Letters · 2021 · https://doi.org/10.1016/j.canlet.2021.03.025

• Association of the Epithelial–Mesenchymal Transition (EMT) with Cisplatin Resistance

  International Journal of Molecular Sciences · 2020 · https://doi.org/10.3390/ijms21114002

• The multifaceted role of reactive oxygen species in tumorigenesis

  Cellular and Molecular Life Sciences · 2020 · 10.1007/s00018-020-03536-5

• Curcumin Delivery Mediated by Bio-Based Nanoparticles: A Review

  Molecules · 2020 · https://doi.org/10.3390/molecules25030689

• Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements

  Biomolecules · 2019 · https://doi.org/10.3390/biom9110735

• The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges

  Cells · 2019 · https://doi.org/10.3390/cells8101118

• Natural product-based nanoformulations for cancer therapy: Opportunities and challenges

  Seminars in Cancer Biology · 2019 · 10.1016/j.semcancer.2019.08.014

• Antioxidant response elements: Discovery, classes, regulation and potential applications

  Redox Biology · 2018 · 10.1016/j.redox.2018.05.002

• Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention

  Pharmacological Research · 2017 · https://doi.org/10.1016/j.phrs.2017.09.014

• The Role of Resveratrol in Cancer Therapy

  International Journal of Molecular Sciences · 2017 · https://doi.org/10.3390/ijms18122589

• Dual role of autophagy in hallmarks of cancer

  Oncogene · 2017 · https://doi.org/10.1038/s41388-017-0046-6

• Resveratrol inhibits STAT3 signaling pathway through the induction of SOCS-1: Role in apoptosis induction and radiosensitization in head and neck tumor cells

  Phytomedicine · 2016 · https://doi.org/10.1016/j.phymed.2016.02.011

• Exosome-Mediated Metastasis: From Epithelial–Mesenchymal Transition to Escape from Immunosurveillance

  Trends in Pharmacological Sciences · 2016 · https://doi.org/10.1016/j.tips.2016.04.006

• Ageing and the telomere connection: An intimate relationship with inflammation

  Ageing Research Reviews · 2015 · 10.1016/j.arr.2015.11.006

• The Multifaceted Role of Curcumin in Cancer Prevention and Treatment

  Molecules · 2015 · https://doi.org/10.3390/molecules20022728

• Targeting the STAT3 signaling pathway in cancer: Role of synthetic and natural inhibitors

  Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · 2014 · https://doi.org/10.1016/j.bbcan.2013.12.005

• The Vascular Endothelium and Human Diseases

  International Journal of Biological Sciences · 2013 · https://doi.org/10.7150/ijbs.7502

• Thymoquinone: Potential cure for inflammatory disorders and cancer

  Biochemical Pharmacology · 2011 · https://doi.org/10.1016/j.bcp.2011.09.029

• Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1

  Oncogene · 2010 · 10.1038/onc.2010.41

• Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer

  International Journal of Cancer · 2010 · https://doi.org/10.1002/ijc.25041

• Targeting transcription factor NF-κB to overcome chemoresistance and radioresistance in cancer therapy

  Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · 2010 · 10.1016/j.bbcan.2010.01.002

• Nuclear Factor-κB Activation: From Bench to Bedside

  Experimental Biology and Medicine · 2008 · 10.3181/0707-mr-196

• TNF: A master switch for inflammation to cancer

  Frontiers in bioscience · 2008 · 10.2741/3066

• Natural products as a gold mine for arthritis treatment

  Current Opinion in Pharmacology · 2007 · 10.1016/j.coph.2007.03.002

• Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism

  Carcinogenesis · 2007 · https://doi.org/10.1093/carcin/bgm123

• Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-κB–regulated antiapoptotic and cell survival gene products in human multiple myeloma cells

  Blood · 2006 · 10.1182/blood-2006-02-003988

• Targeting Signal‐Transducer‐and‐Activator‐of‐Transcription‐3 for Prevention and Therapy of Cancer

  Annals of the New York Academy of Sciences · 2006 · 10.1196/annals.1378.063

• Inflammation and cancer: How hot is the link?

  Biochemical Pharmacology · 2006 · https://doi.org/10.1016/j.bcp.2006.06.029

• Curcumin: Getting Back to the Roots

  Annals of the New York Academy of Sciences · 2005 · https://doi.org/10.1196/annals.1352.010

Current projects

No projects listed.