Feng Chen

Research interests

Publications

• Circular RNA vaccines against SARS-CoV-2 and emerging variants

  Cell · 2022 · https://doi.org/10.1016/j.cell.2022.03.044

• Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma

  JAMA · 2020 · https://doi.org/10.1001/jama.2020.4783

• Targeted mRNA demethylation using an engineered dCas13b-ALKBH5 fusion protein

  Nucleic Acids Research · 2020 · https://doi.org/10.1093/nar/gkaa269

• N6-methyladenosine regulates glycolysis of cancer cells through PDK4

  Nature Communications · 2020 · https://doi.org/10.1038/s41467-020-16306-5

• Assessing ACE2 expression patterns in lung tissues in the pathogenesis of COVID-19

  Journal of Autoimmunity · 2020 · https://doi.org/10.1016/j.jaut.2020.102463

• ACOD1 in immunometabolism and disease

  Cellular and Molecular Immunology · 2020 · https://doi.org/10.1038/s41423-020-0489-5

• m6A-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1

  Molecular Cancer · 2019 · https://doi.org/10.1186/s12943-019-1014-2

• Widespread Polycistronic Transcripts in Fungi Revealed by Single-Molecule mRNA Sequencing

  PLoS ONE · 2015 · https://doi.org/10.1371/journal.pone.0132628

• Integrative Genomic Approaches Highlight a Family of Parasite-Specific Kinases that Regulate Host Responses

  Cell Host & Microbe · 2010 · https://doi.org/10.1016/j.chom.2010.07.004

• A single-base resolution map of an archaeal transcriptome

  Genome Research · 2009 · https://doi.org/10.1101/gr.100396.109

• A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea

  Nature · 2009 · https://doi.org/10.1038/nature08656

• Rapid whole-genome mutational profiling using next-generation sequencing technologies

  Genome Research · 2008 · https://doi.org/10.1101/gr.077776.108

• Vasopressin-stimulated Increase in Phosphorylation at Ser269 Potentiates Plasma Membrane Retention of Aquaporin-2

  Journal of Biological Chemistry · 2008 · https://doi.org/10.1074/jbc.m803074200

• Genomic-scale prioritization of drug targets: the TDR Targets database

  Nature Reviews Drug Discovery · 2008 · https://doi.org/10.1038/nrd2684

• Assessing Performance of Orthology Detection Strategies Applied to Eukaryotic Genomes

  PLoS ONE · 2007 · https://doi.org/10.1371/journal.pone.0000383

• Statistical analysis of real-time PCR data

  BMC Bioinformatics · 2006 · https://doi.org/10.1186/1471-2105-7-85

• Sequencing and Analysis of Neanderthal Genomic DNA

  Science · 2006 · https://doi.org/10.1126/science.1131412

• OrthoMCL-DB: querying a comprehensive multi-species collection of ortholog groups

  Nucleic Acids Research · 2005 · https://doi.org/10.1093/nar/gkj123

• A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac

  Nature Genetics · 2004 · https://doi.org/10.1038/ng1314

• The Small Heat Shock Protein αB-crystallin Negatively Regulates Apoptosis during Myogenic Differentiation by Inhibiting Caspase-3 Activation

  Journal of Biological Chemistry · 2002 · https://doi.org/10.1074/jbc.m201770200

• The Small Heat Shock Protein αB-Crystallin Negatively Regulates Cytochrome c- and Caspase-8-dependent Activation of Caspase-3 by Inhibiting Its Autoproteolytic Maturation

  Journal of Biological Chemistry · 2001 · https://doi.org/10.1074/jbc.c100107200

• Tau Filament Formation in Transgenic Mice Expressing P301L Tau

  Journal of Biological Chemistry · 2001 · https://doi.org/10.1074/jbc.m006531200

• Inhibition of RNA polymerase II as a trigger for the p53 response

  Oncogene · 1999 · https://doi.org/10.1038/sj.onc.1202356

Current projects

No projects listed.