Lee Cooper

Research interests

Publications

• A population-level digital histologic biomarker for enhanced prognosis of invasive breast cancer

  Nature Medicine · 2023 · 10.1038/s41591-023-02643-7

• Glioma progression is shaped by genetic evolution and microenvironment interactions

  Cell · 2022 · https://doi.org/10.1016/j.cell.2022.04.038

• MONAI: An open-source framework for deep learning in healthcare

  arXiv (Cornell University) · 2022 · 10.48550/arxiv.2211.02701

• An expanded universe of cancer targets

  Cell · 2021 · 10.1016/j.cell.2021.02.020

• Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer

  npj Breast Cancer · 2020 · https://doi.org/10.1038/s41523-020-0156-0

• Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group

  npj Breast Cancer · 2020 · https://doi.org/10.1038/s41523-020-0154-2

• Structured crowdsourcing enables convolutional segmentation of histology images

  Bioinformatics · 2019 · 10.1093/bioinformatics/btz083

• Deep learning enables robust assessment and selection of human blastocysts after in vitro fertilization

  npj Digital Medicine · 2019 · https://doi.org/10.1038/s41746-019-0096-y

• Predicting cancer outcomes from histology and genomics using convolutional networks

  Proceedings of the National Academy of Sciences · 2018 · https://doi.org/10.1073/pnas.1717139115

• Image-guided genomics of phenotypically heterogeneous populations reveals vascular signalling during symbiotic collective cancer invasion

  Nature Communications · 2017 · 10.1038/ncomms15078

• Correction: Corrigendum: The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies

  Nature Communications · 2017 · https://doi.org/10.1038/ncomms15350

• T2–FLAIR Mismatch, an Imaging Biomarker for IDH and 1p/19q Status in Lower-grade Gliomas: A TCGA/TCIA Project

  Clinical Cancer Research · 2017 · 10.1158/1078-0432.ccr-17-0560

• PanCancer insights from The Cancer Genome Atlas: the pathologist's perspective

  The Journal of Pathology · 2017 · 10.1002/path.5028

• Predicting clinical outcomes from large scale cancer genomic profiles with deep survival models

  Scientific Reports · 2017 · 10.1038/s41598-017-11817-6

• The Digital Slide Archive: A Software Platform for Management, Integration, and Analysis of Histology for Cancer Research

  Cancer Research · 2017 · 10.1158/0008-5472.can-17-0629

• The OncoPPi network of cancer-focused protein–protein interactions to inform biological insights and therapeutic strategies

  Nature Communications · 2017 · 10.1038/ncomms14356

• Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

  Cell · 2016 · https://doi.org/10.1016/j.cell.2015.12.028

• MR Imaging Predictors of Molecular Profile and Survival: Multi-institutional Study of the TCGA Glioblastoma Data Set

  Radiology · 2013 · https://doi.org/10.1148/radiol.13120118

• Tumor-Infiltrating Lymphocytes in Glioblastoma Are Associated with Specific Genomic Alterations and Related to Transcriptional Class

  Clinical Cancer Research · 2013 · 10.1158/1078-0432.ccr-13-0551

• Cancer Digital Slide Archive: an informatics resource to support integrated in silico analysis of TCGA pathology data

  Journal of the American Medical Informatics Association · 2013 · 10.1136/amiajnl-2012-001469

• The Tumor Microenvironment Strongly Impacts Master Transcriptional Regulators and Gene Expression Class of Glioblastoma

  American Journal Of Pathology · 2012 · 10.1016/j.ajpath.2012.01.040

• The Proneural Molecular Signature Is Enriched in Oligodendrogliomas and Predicts Improved Survival among Diffuse Gliomas

  PLoS ONE · 2010 · 10.1371/journal.pone.0012548

• AZD2171: A Highly Potent, Orally Bioavailable, Vascular Endothelial Growth Factor Receptor-2 Tyrosine Kinase Inhibitor for the Treatment of Cancer

  Cancer Research · 2005 · https://doi.org/10.1158/0008-5472.can-04-4409

• An 2,3 sialyltransferase (ST3Gal I) is elevated in primary breast carcinomas

  Glycobiology · 1999 · 10.1093/glycob/9.12.1307

Current projects

No projects listed.