Yashpal S. Kanwar

Research interests

Publications

• Myo-inositol oxygenase expression profile modulates pathogenic ferroptosis in the renal proximal tubule

  Journal of Clinical Investigation · 2019 · 10.1172/jci129903

• Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis

  Redox Biology · 2018 · 10.1016/j.redox.2018.02.013

• Disruption of Renal Tubular Mitochondrial Quality Control by Myo-Inositol Oxygenase in Diabetic Kidney Disease

  Journal of the American Society of Nephrology · 2014 · 10.1681/asn.2014050457

• Resolution of Recurrent Focal Segmental Glomerulosclerosis after Retransplantation

  New England Journal of Medicine · 2012 · 10.1056/nejmc1202500

• A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy

  Annual Review of Pathology Mechanisms of Disease · 2011 · https://doi.org/10.1146/annurev.pathol.4.110807.092150

• Oxidative Stress in Diabetic Nephropathy

  Current Medicinal Chemistry · 2010 · 10.2174/092986710793348581

• Diabetic Nephropathy: Mechanisms of Renal Disease Progression

  Experimental Biology and Medicine · 2008 · 10.3181/0705-mr-134

• Amelioration of progressive renal injury by genetic manipulation of Klotho gene

  Proceedings of the National Academy of Sciences · 2007 · 10.1073/pnas.0611079104

• ACE2 inhibition worsens glomerular injury in association with increased ACE expression in streptozotocin-induced diabetic mice

  Kidney International · 2007 · 10.1038/sj.ki.5002373

• Blockade of Vascular Endothelial Growth Factor Signaling Ameliorates Diabetic Albuminuria in Mice

  Journal of the American Society of Nephrology · 2006 · 10.1681/asn.2006010064

• Visceral adipose tissue-derived serine protease inhibitor: A unique insulin-sensitizing adipocytokine in obesity

  Proceedings of the National Academy of Sciences · 2005 · https://doi.org/10.1073/pnas.0504703102

• Neph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability

  Journal of Clinical Investigation · 2003 · 10.1172/jci18242

• 3-Hydroxy-3-methylglutaryl CoA reductase inhibitors prevent high glucose-induced proliferation of mesangial cells via modulation of Rho GTPase/ p21 signaling pathway: Implications for diabetic nephropathy

  Proceedings of the National Academy of Sciences · 2002 · 10.1073/pnas.122228799

• Collectrin, a Collecting Duct-specific Transmembrane Glycoprotein, Is a Novel Homolog of ACE2 and Is Developmentally Regulated in Embryonic Kidneys

  Journal of Biological Chemistry · 2001 · 10.1074/jbc.m006723200

• Isolation and Characterization of Peroxisome Proliferator-activated Receptor (PPAR) Interacting Protein (PRIP) as a Coactivator for PPAR

  Journal of Biological Chemistry · 2000 · 10.1074/jbc.275.18.13510

• Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin.

  Journal of Clinical Investigation · 1997 · 10.1172/jci119429

• Identification and Characterization of Galectin-9, a Novel β-Galactoside-binding Mammalian Lectin

  Journal of Biological Chemistry · 1997 · 10.1074/jbc.272.9.6078

• Identification of a receptor for protein import into chloroplasts and its localization to envelope contact zones

  Nature · 1988 · 10.1038/331232a0

• Biophysiology of glomerular filtration and proteinuria.

  PubMed · 1984

• Removal of sulfated (heparan sulfate) or nonsulfated (hyaluronic acid) glycosaminoglycans results in increased permeability of the glomerular basement membrane to 125I-bovine serum albumin.

  PubMed · 1982

• Partial characterization of newly synthesized proteoglycans isolated from the glomerular basement membrane.

  The Journal of Cell Biology · 1981 · 10.1083/jcb.90.2.527

• Increased permeability of the glomerular basement membrane to ferritin after removal of glycosaminoglycans (heparan sulfate) by enzyme digestion.

  The Journal of Cell Biology · 1980 · 10.1083/jcb.86.2.688

• Isolation of glycosaminoglycans (heparan sulfate) from glomerular basement membranes

  Proceedings of the National Academy of Sciences · 1979 · 10.1073/pnas.76.9.4493

• Anionic sites in the glomerular basement membrane. In vivo and in vitro localization to the laminae rarae by cationic probes.

  The Journal of Cell Biology · 1979 · 10.1083/jcb.81.1.137

• Presence of heparan sulfate in the glomerular basement membrane

  Proceedings of the National Academy of Sciences · 1979 · 10.1073/pnas.76.3.1303

Current projects

No projects listed.