Denise Scholtens

Research interests

Publications

• Associations of Maternal Cardiovascular Health in Pregnancy With Offspring Cardiovascular Health in Early Adolescence

  JAMA · 2021 · 10.1001/jama.2021.0247

• Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): Maternal Gestational Diabetes Mellitus and Childhood Glucose Metabolism

  Diabetes Care · 2019 · 10.2337/dc18-1646

• Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): Maternal Gestational Diabetes Mellitus and Childhood Glucose Metabolism

  Diabetes Care · 2019 · 10.2337/dc18-1646

• The Coincidence Between Increasing Age, Immunosuppression, and the Incidence of Patients With Glioblastoma

  Frontiers in Pharmacology · 2019 · 10.3389/fphar.2019.00200

• Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): Maternal Glycemia and Childhood Glucose Metabolism

  Diabetes Care · 2019 · 10.2337/dc18-2021

• Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): Maternal Glycemia and Childhood Glucose Metabolism

  Diabetes Care · 2019 · 10.2337/dc18-2021

• Maternal glucose levels during pregnancy and childhood adiposity in the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study

  Diabetologia · 2019 · 10.1007/s00125-018-4809-6

• Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration

  Nature Communications · 2019 · 10.1038/s41467-019-11881-8

• Association of Gestational Diabetes With Maternal Disorders of Glucose Metabolism and Childhood Adiposity

  JAMA · 2018 · 10.1001/jama.2018.11628

• IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma

  Clinical Cancer Research · 2018 · 10.1158/1078-0432.ccr-17-3573

• Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

  Human Molecular Genetics · 2018 · 10.1093/hmg/ddx429

• Maternal BMI and Glycemia Impact the Fetal Metabolome

  Diabetes Care · 2017 · 10.2337/dc16-2452

• Transversions have larger regulatory effects than transitions

  BMC Genomics · 2017 · 10.1186/s12864-017-3785-4

• Genome-wide associations for birth weight and correlations with adult disease

  Nature · 2016 · https://doi.org/10.1038/nature19806

• Genetics of Gestational Diabetes Mellitus and Maternal Metabolism

  Current Diabetes Reports · 2016 · 10.1007/s11892-015-0709-z

• Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight

  JAMA · 2016 · 10.1001/jama.2016.1975

• Maternal and Neonatal Morbidity for Women Who Would Be Added to the Diagnosis of GDM Using IADPSG Criteria: A Secondary Analysis of the Hyperglycemia and Adverse Pregnancy Outcome Study

  Diabetes Care · 2016 · 10.2337/dc16-1194

• Massively parallel quantification of the regulatory effects of noncoding genetic variation in a human cohort

  Genome Research · 2015 · 10.1101/gr.190090.115

• Coordinated regulatory variation associated with gestational hyperglycaemia regulates expression of the novel hexokinase HKDC1

  Nature Communications · 2015 · 10.1038/ncomms7069

• Maternal short-chain fatty acids are associated with metabolic parameters in mothers and newborns

  Translational research · 2014 · 10.1016/j.trsl.2014.01.012

• Metabolomics Reveals Broad-Scale Metabolic Perturbations in Hyperglycemic Mothers During Pregnancy

  Diabetes Care · 2013 · 10.2337/dc13-0989

• Expression of RORγt Marks a Pathogenic Regulatory T Cell Subset in Human Colon Cancer

  Science Translational Medicine · 2012 · 10.1126/scitranslmed.3004566

• NFKBIA Deletion in Glioblastomas

  New England Journal of Medicine · 2010 · 10.1056/nejmoa1006312

• A Network Model of a Cooperative Genetic Landscape in Brain Tumors

  JAMA · 2009 · 10.1001/jama.2009.997

• Surgical resection of the primary tumor, chest wall control, and survival in women with metastatic breast cancer

  Cancer · 2008 · 10.1002/cncr.23870

Current projects

No projects listed.