Peter S. Nelson

Research interests

Publications

• Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer

  Nature Communications · 2021 · https://doi.org/10.1038/s41467-021-26042-z

• Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress

  Cell Reports · 2020 · https://doi.org/10.1016/j.celrep.2020.107669

• Association of Clonal Hematopoiesis in DNA Repair Genes With Prostate Cancer Plasma Cell-free DNA Testing Interference

  JAMA Oncology · 2020 · https://doi.org/10.1001/jamaoncol.2020.5161

• Genomic correlates of clinical outcome in advanced prostate cancer

  Proceedings of the National Academy of Sciences · 2019 · https://doi.org/10.1073/pnas.1902651116

• Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer

  Journal of Clinical Investigation · 2019 · https://doi.org/10.1172/jci128212

• ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer

  Cancer Cell · 2019 · https://doi.org/10.1016/j.ccell.2019.01.008

• A phase I study of niclosamide in combination with enzalutamide in men with castration-resistant prostate cancer

  PLoS ONE · 2018 · https://doi.org/10.1371/journal.pone.0198389

• The long tail of oncogenic drivers in prostate cancer

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0078-z

• Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing

  Cell · 2018 · https://doi.org/10.1016/j.cell.2018.05.036

• Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling

  Cancer Cell · 2017 · https://doi.org/10.1016/j.ccell.2017.09.003

• Trial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3

  Journal of Clinical Oncology · 2016 · 10.1200/jco.2015.64.2702

• Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer

  Nature Medicine · 2016 · https://doi.org/10.1038/nm.4053

• Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

  New England Journal of Medicine · 2016 · https://doi.org/10.1056/nejmoa1603144

• Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015

  Annals of Oncology · 2015 · https://doi.org/10.1093/annonc/mdv257

• Integrative Clinical Genomics of Advanced Prostate Cancer

  Cell · 2015 · 10.1016/j.cell.2015.05.001

• Biallelic Inactivation of BRCA2 in Platinum-sensitive Metastatic Castration-resistant Prostate Cancer

  European Urology · 2015 · https://doi.org/10.1016/j.eururo.2015.11.022

• Circulating microRNA Profiling Identifies a Subset of Metastatic Prostate Cancer Patients with Evidence of Cancer-Associated Hypoxia

  PLoS ONE · 2013 · https://doi.org/10.1371/journal.pone.0069239

• The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression

  Journal of Clinical Investigation · 2010 · https://doi.org/10.1172/jci44239

• New Nomenclature for the Human Tissue Kallikrein Gene Family

  Clinical Chemistry · 2000 · https://doi.org/10.1093/clinchem/46.11.1855

• Monitoring gene expression profile changes in ovarian carcinomas using cDNA microarray

  Gene · 1999 · https://doi.org/10.1016/s0378-1119(99)00035-9

Current projects

No projects listed.