Ian B. Hickie

Research interests

Publications

• Genomics yields biological and phenotypic insights into bipolar disorder

  Nature · 2025 · https://doi.org/10.1038/s41586-024-08468-9

• The Lancet Psychiatry Commission on youth mental health

  The Lancet Psychiatry · 2024 · https://doi.org/10.1016/s2215-0366(24)00163-9

• Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder

  Nature Genetics · 2024 · https://doi.org/10.1038/s41588-024-01707-9

• Towards a youth mental health paradigm: a perspective and roadmap

  Molecular Psychiatry · 2023 · https://doi.org/10.1038/s41380-023-02202-z

• Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

  Nature Mental Health · 2023 · https://doi.org/10.1038/s44220-023-00034-y

• Genetic diversity fuels gene discovery for tobacco and alcohol use

  Nature · 2022 · https://doi.org/10.1038/s41586-022-05477-4

• Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3–90 years

  Human Brain Mapping · 2021 · https://doi.org/10.1002/hbm.25364

• Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

  Nature Genetics · 2019 · https://doi.org/10.1038/s41588-018-0307-5

• Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing

  Genome Medicine · 2019 · https://doi.org/10.1186/s13073-019-0667-1

• Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0090-3

• Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group

  Molecular Psychiatry · 2017 · https://doi.org/10.1038/mp.2017.170

• Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group

  Molecular Psychiatry · 2016 · https://doi.org/10.1038/mp.2016.60

• Effect of ω-3 Polyunsaturated Fatty Acids in Young People at Ultrahigh Risk for Psychotic Disorders

  JAMA Psychiatry · 2016 · https://doi.org/10.1001/jamapsychiatry.2016.2902

• Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group

  Molecular Psychiatry · 2015 · https://doi.org/10.1038/mp.2015.69

• Biomarkers and clinical staging in psychiatry

  World Psychiatry · 2014 · https://doi.org/10.1002/wps.20144

• A mega-analysis of genome-wide association studies for major depressive disorder

  Molecular Psychiatry · 2012 · https://doi.org/10.1038/mp.2012.21

• A Systematic Review of the Impact of Adherence on the Effectiveness of e-Therapies

  Journal of Medical Internet Research · 2011 · 10.2196/jmir.1772

• Intervention in Individuals at Ultra-High Risk for Psychosis

  The Journal of Clinical Psychiatry · 2009 · https://doi.org/10.4088/jcp.08r04472

• Clinical Staging of Psychiatric Disorders: A Heuristic Framework for Choosing Earlier, Safer and more Effective Interventions

  Australian & New Zealand Journal of Psychiatry · 2006 · 10.1080/j.1440-1614.2006.01860.x

• Reduced hippocampal volumes and memory loss in patients with early- and late-onset depression

  The British Journal of Psychiatry · 2005 · https://doi.org/10.1192/bjp.186.3.197

• Cognitive function in depression: a distinct pattern of frontal impairment in melancholia?

  Psychological Medicine · 1999 · https://doi.org/10.1017/s0033291798007788

• The Psychiatric Status of Patients with the Chronic Fatigue Syndrome

  The British Journal of Psychiatry · 1990 · https://doi.org/10.1192/bjp.156.4.534

Current projects

No projects listed.