Lee‐Ming Chuang

Research interests

Publications

• Genetic drivers of heterogeneity in type 2 diabetes pathophysiology

  Nature · 2024 · https://doi.org/10.1038/s41586-024-07019-6

• Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

  Nature Genetics · 2022 · https://doi.org/10.1038/s41588-022-01058-3

• A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

  Nature Genetics · 2021 · https://doi.org/10.1038/s41588-021-00935-7

• Identification of type 2 diabetes loci in 433,540 East Asian individuals

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2263-3

• Lifestyle Intervention and Medical Management With vs Without Roux-en-Y Gastric Bypass and Control of Hemoglobin A 1c , LDL Cholesterol, and Systolic Blood Pressure at 5 Years in the Diabetes Surgery Study

  JAMA · 2018 · https://doi.org/10.1001/jama.2017.20813

• Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

  Nature Communications · 2018 · https://doi.org/10.1038/s41467-018-05747-8

• Roux-en-Y gastric bypass for diabetes (the Diabetes Surgery Study): 2-year outcomes of a 5-year, randomised, controlled trial

  The Lancet Diabetes & Endocrinology · 2015 · https://doi.org/10.1016/s2213-8587(15)00089-3

• Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

  Nature Genetics · 2014 · https://doi.org/10.1038/ng.2897

• Metabolic profiles and treatment gaps in young-onset type 2 diabetes in Asia (the JADE programme): a cross-sectional study of a prospective cohort

  The Lancet Diabetes & Endocrinology · 2014 · 10.1016/s2213-8587(14)70137-8

• Association Between Plasma Triglycerides and High-Density Lipoprotein Cholesterol and Microvascular Kidney Disease and Retinopathy in Type 2 Diabetes Mellitus

  Circulation · 2013 · 10.1161/circulationaha.113.002529

• Roux-en-Y Gastric Bypass vs Intensive Medical Management for the Control of Type 2 Diabetes, Hypertension, and Hyperlipidemia

  JAMA · 2013 · https://doi.org/10.1001/jama.2013.5835

• Measurement of Waist Circumference

  Diabetes Care · 2012 · 10.2337/dc12-1452

• Predicting the Glycemic Response to Gastric Bypass Surgery in Patients With Type 2 Diabetes

  Diabetes Care · 2012 · 10.2337/dc12-0779

• Incidence and prevalence rates of diabetes mellitus in Taiwan: Analysis of the 2000–2009 Nationwide Health Insurance database

  Journal of the Formosan Medical Association · 2012 · 10.1016/j.jfma.2012.09.014

• Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians

  Diabetologia · 2011 · 10.1007/s00125-011-2370-7

• Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

  Nature Genetics · 2011 · https://doi.org/10.1038/ng.1019

• Association of thiazolidinediones with liver cancer and colorectal cancer in type 2 diabetes mellitus

  Hepatology · 2011 · 10.1002/hep.25509

• A Genome-Wide Association Study Identifies Susceptibility Variants for Type 2 Diabetes in Han Chinese

  PLoS Genetics · 2010 · 10.1371/journal.pgen.1000847

• Common Variation in the Fat Mass and Obesity-Associated (FTO) Gene Confers Risk of Obesity and Modulates BMI in the Chinese Population

  Diabetes · 2008 · 10.2337/db08-0377

• Association Study of the Genetic Polymorphisms of the Transcription Factor 7-Like 2 (TCF7L2) Gene and Type 2 Diabetes in the Chinese Population

  Diabetes · 2007 · 10.2337/db07-0421

• Low Birth Weight and High Birth Weight Infants Are Both at an Increased Risk to Have Type 2 Diabetes Among Schoolchildren in Taiwan

  Diabetes Care · 2003 · 10.2337/diacare.26.2.343

• Plasma Adiponectin Levels in Overweight and Obese Asians

  Obesity Research · 2002 · 10.1038/oby.2002.150

• Synthetic Peroxisome Proliferator-Activated Receptor-γ Agonist, Rosiglitazone, Increases Plasma Levels of Adiponectin in Type 2 Diabetic Patients

  Diabetes Care · 2002 · 10.2337/diacare.25.2.376

• Weight Reduction Increases Plasma Levels of an Adipose-Derived Anti-Inflammatory Protein, Adiponectin

  The Journal of Clinical Endocrinology & Metabolism · 2001 · 10.1210/jcem.86.8.7741

• Insulin sensitivity is inversely correlated with plasma intact parathyroid hormone level

  Metabolism · 2000 · 10.1053/meta.2000.17708

Current projects

No projects listed.