Kuo‐Hsiung Lee

Research interests

Publications

• Killing tumor-associated bacteria with a liposomal antibiotic generates neoantigens that induce anti-tumor immune responses

  Nature Biotechnology · 2023 · 10.1038/s41587-023-01957-8

• Biologically active isoquinoline alkaloids covering 2014–2018

  Medicinal Research Reviews · 2020 · 10.1002/med.21703

• Biologically active quinoline and quinazoline alkaloids part I

  Medicinal Research Reviews · 2017 · https://doi.org/10.1002/med.21466

• Clerodane diterpenes: sources, structures, and biological activities

  Natural Product Reports · 2016 · 10.1039/c5np00137d

• Perspectives on Biologically Active Camptothecin Derivatives

  Medicinal Research Reviews · 2015 · 10.1002/med.21342

• Recent discovery of plant-derived anti-diabetic natural products

  Natural Product Reports · 2012 · 10.1039/c2np00074a

• Biosynthesis, total syntheses, and antitumor activity of tanshinones and their analogs as potential therapeutic agents

  Natural Product Reports · 2011 · 10.1039/c0np00035c

• Discovery and Development of Natural Product-Derived Chemotherapeutic Agents Based on a Medicinal Chemistry Approach

  Journal of Natural Products · 2010 · 10.1021/np900821e

• New developments in the chemistry and biology of the bioactive constituents of tanshen

  Medicinal Research Reviews · 2006 · https://doi.org/10.1002/med.20077

• Antitumor Agents. 239. Isolation, Structure Elucidation, Total Synthesis, and Anti-Breast Cancer Activity of Neo-tanshinlactone from Salvia miltiorrhiza

  Journal of Medicinal Chemistry · 2004 · 10.1021/jm040112r

• Anti-HIV benzylisoquinoline alkaloids and flavonoids from the leaves of Nelumbo nucifera, and structure–activity correlations with related alkaloids

  Bioorganic & Medicinal Chemistry · 2004 · https://doi.org/10.1016/j.bmc.2004.10.020

• Recent progress in the development of coumarin derivatives as potent anti‐HIV agents

  Medicinal Research Reviews · 2003 · https://doi.org/10.1002/med.10034

• Anti-AIDS agents 54. A potent anti-HIV chalcone and flavonoids from genus Desmos

  Bioorganic & Medicinal Chemistry Letters · 2003 · 10.1016/s0960-894x(03)00197-5

• Rational selection of training and test sets for the development of validated QSAR models

  Journal of Computer-Aided Molecular Design · 2003 · https://doi.org/10.1023/a:1025386326946

• Antitumor Agents. 217. Curcumin Analogues as Novel Androgen Receptor Antagonists with Potential as Anti-Prostate Cancer Agents

  Journal of Medicinal Chemistry · 2002 · 10.1021/jm020200g

• Antitumor Agents. Part 204: Synthesis and Biological Evaluation of Substituted 2-Aryl Quinazolinones

  Bioorganic & Medicinal Chemistry Letters · 2001 · 10.1016/s0960-894x(01)00190-1

• Anti-AIDS Agents. 48. Anti-HIV Activity of Moronic Acid Derivatives and the New Melliferone-Related Triterpenoid Isolated from Brazilian Propolis

  Journal of Natural Products · 2001 · 10.1021/np010211x

• Isolation of rhododaurichromanic acid B and the anti-HIV principles rhododaurichromanic acid A and rhododaurichromenic acid from Rhododendron dauricum

  Tetrahedron · 2001 · 10.1016/s0040-4020(00)01144-3

• 6-Alkylamino- and 2,3-Dihydro-3‘-methoxy-2-phenyl-4-quinazolinones and Related Compounds: Their Synthesis, Cytotoxicity, and Inhibition of Tubulin Polymerization

  Journal of Medicinal Chemistry · 2000 · 10.1021/jm000151c

• Antitumor agents. Part 202: Novel 2′-amino chalcones: design, synthesis and biological evaluation

  Bioorganic & Medicinal Chemistry Letters · 2000 · 10.1016/s0960-894x(00)00072-x

• Antitumor Agents. 181. Synthesis and Biological Evaluation of 6,7,2‘,3‘,4‘-Substituted-1,2,3,4-tetrahydro-2-phenyl-4-quinolones as a New Class of Antimitotic Antitumor Agents

  Journal of Medicinal Chemistry · 1998 · 10.1021/jm9707479

• Anti-AIDS Agents. 30. Anti-HIV Activity of Oleanolic Acid, Pomolic Acid, and Structurally Related Triterpenoids

  Journal of Natural Products · 1998 · 10.1021/np9800710

• Betulinic Acid and Dihydrobetulinic Acid Derivatives as Potent Anti-HIV Agents

  Journal of Medicinal Chemistry · 1996 · 10.1021/jm950922q

• Sesquiterpene Antitumor Agents: Inhibitors of Cellular Metabolism

  Science · 1977 · 10.1126/science.191909

• Cytotoxicity of sesquiterpene lactones.

  PubMed · 1971

Current projects

No projects listed.