Kai Zacharowski

Research interests

Publications

• Management of severe peri-operative bleeding: Guidelines from the European Society of Anaesthesiology and Intensive Care

  European Journal of Anaesthesiology · 2023 · 10.1097/eja.0000000000001803

• 2022 ESC Guidelines on cardiovascular assessment and management of patients undergoing non-cardiac surgery

  European Heart Journal · 2022 · https://doi.org/10.1093/eurheartj/ehac270

• Long-term cardiac pathology in individuals with mild initial COVID-19 illness

  Nature Medicine · 2022 · 10.1038/s41591-022-02000-0

• Association of Intravenous Tranexamic Acid With Thromboembolic Events and Mortality

  JAMA Surgery · 2021 · 10.1001/jamasurg.2021.0884

• Insight into ECMO, mortality and ARDS: a nationwide analysis of 45,647 ECMO runs

  Critical Care · 2021 · 10.1186/s13054-021-03463-2

• Identification and validation of biomarkers of persistent acute kidney injury: the RUBY study

  Intensive Care Medicine · 2020 · 10.1007/s00134-019-05919-0

• Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study)

  Intensive Care Medicine · 2018 · 10.1007/s00134-018-5143-7

• Multimodal Patient Blood Management Program Based on a Three-pillar Strategy

  Annals of Surgery · 2018 · 10.1097/sla.0000000000003095

• Neutrophil transfer of miR-223 to lung epithelial cells dampens acute lung injury in mice

  Science Translational Medicine · 2017 · 10.1126/scitranslmed.aah5360

• Management of severe perioperative bleeding

  European Journal of Anaesthesiology · 2017 · 10.1097/eja.0000000000000630

• Patient Blood Management Bundles to Facilitate Implementation

  Transfusion Medicine Reviews · 2016 · 10.1016/j.tmrv.2016.05.012

• Patient Blood Management is Associated With a Substantial Reduction of Red Blood Cell Utilization and Safe for Patient's Outcome

  Annals of Surgery · 2016 · 10.1097/sla.0000000000001747

• A Multicenter Trial of Remote Ischemic Preconditioning for Heart Surgery

  New England Journal of Medicine · 2015 · 10.1056/nejmoa1413579

• Rapid Diagnosis of Infection in the Critically Ill, a Multicenter Study of Molecular Detection in Bloodstream Infections, Pneumonia, and Sterile Site Infections*

  Critical Care Medicine · 2015 · 10.1097/ccm.0000000000001249

• Severe Ebola virus disease with vascular leakage and multiorgan failure: treatment of a patient in intensive care

  The Lancet · 2014 · 10.1016/s0140-6736(14)62384-9

• Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury

  Critical Care · 2013 · https://doi.org/10.1186/cc12503

• Point-of-Care Testing

  Anesthesiology · 2012 · 10.1097/aln.0b013e318264c644

• Novel Aspects of Fibrin(ogen) Fragments during Inflammation

  Molecular Medicine · 2011 · 10.2119/molmed.2010.00146

• Biomarkers of endothelial dysfunction: can they help us deciphering systemic inflammation and sepsis?

  Biomarkers · 2011 · 10.3109/1354750x.2011.587893

• Tranexamic acid partially improves platelet function in patients treated with dual antiplatelet therapy

  European Journal of Anaesthesiology · 2010 · 10.1097/eja.0b013e32834050ab

• Inflammatory response and cardioprotection during open‐heart surgery: the importance of anaesthetics

  British Journal of Pharmacology · 2007 · 10.1038/sj.bjp.0707526

• Clinical chemistry reference database for Wistar rats and C57/BL6 mice

  Biological Chemistry · 2007 · 10.1515/bc.2007.061

• Toll-like receptor 4 plays a crucial role in the immune–adrenal response to systemic inflammatory response syndrome

  Proceedings of the National Academy of Sciences · 2006 · 10.1073/pnas.0601527103

• The fibrin-derived peptide Bβ15–42 protects the myocardium against ischemia-reperfusion injury

  Nature Medicine · 2005 · 10.1038/nm1198

• Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat

  Kidney International · 2000 · 10.1046/j.1523-1755.2000.00212.x

Current projects

No projects listed.