Jun Yu

Research interests

Publications

• Cellular zinc metabolism and zinc signaling: from biological functions to diseases and therapeutic targets

  Signal Transduction and Targeted Therapy · 2024 · https://doi.org/10.1038/s41392-023-01679-y

• Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites

  Gut · 2020 · https://doi.org/10.1136/gutjnl-2019-319664

• Peptostreptococcus anaerobius promotes colorectal carcinogenesis and modulates tumour immunity

  Nature Microbiology · 2019 · https://doi.org/10.1038/s41564-019-0541-3

• Multi-cohort analysis of colorectal cancer metagenome identified altered bacteria across populations and universal bacterial markers

  Microbiome · 2018 · https://doi.org/10.1186/s40168-018-0451-2

• Association Between Bacteremia From Specific Microbes and Subsequent Diagnosis of Colorectal Cancer

  Gastroenterology · 2018 · https://doi.org/10.1053/j.gastro.2018.04.028

• Alterations in Enteric Virome Are Associated With Colorectal Cancer and Survival Outcomes

  Gastroenterology · 2018 · https://doi.org/10.1053/j.gastro.2018.04.018

• Peptostreptococcus anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice

  Gastroenterology · 2017 · https://doi.org/10.1053/j.gastro.2017.01.009

• Gavage of Fecal Samples From Patients With Colorectal Cancer Promotes Intestinal Carcinogenesis in Germ-Free and Conventional Mice

  Gastroenterology · 2017 · https://doi.org/10.1053/j.gastro.2017.08.022

• Bacteriophage transfer during faecal microbiota transplantation in Clostridium difficile infection is associated with treatment outcome

  Gut · 2017 · https://doi.org/10.1136/gutjnl-2017-313952

• Fecal Bacteria Act as Novel Biomarkers for Noninvasive Diagnosis of Colorectal Cancer

  Clinical Cancer Research · 2016 · https://doi.org/10.1158/1078-0432.ccr-16-1599

• Quantitation of faecal Fusobacterium improves faecal immunochemical test in detecting advanced colorectal neoplasia

  Gut · 2016 · https://doi.org/10.1136/gutjnl-2016-312766

• A catalog of the mouse gut metagenome

  Nature Biotechnology · 2015 · https://doi.org/10.1038/nbt.3353

• Gut mucosal microbiome across stages of colorectal carcinogenesis

  Nature Communications · 2015 · https://doi.org/10.1038/ncomms9727

• Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer

  Gut · 2015 · https://doi.org/10.1136/gutjnl-2015-309800

• Carbonic anhydrase IV inhibits colon cancer development by inhibiting the Wnt signalling pathway through targeting the WTAP–WT1–TBL1 axis

  Gut · 2015 · https://doi.org/10.1136/gutjnl-2014-308614

• Targeted next‐generation sequencing of cancer genes dissects the molecular profiles of intraductal papillary neoplasms of the pancreas

  The Journal of Pathology · 2014 · https://doi.org/10.1002/path.4344

• Improved survival of gastric cancer with tumour Epstein–Barr virus positivity: an international pooled analysis

  Gut · 2013 · https://doi.org/10.1136/gutjnl-2013-304531

• Molecular Characterization of the Fecal Microbiota in Patients with Nonalcoholic Steatohepatitis – A Longitudinal Study

  PLoS ONE · 2013 · https://doi.org/10.1371/journal.pone.0062885

• Detection of miR-92a and miR-21 in stool samples as potential screening biomarkers for colorectal cancer and polyps

  Gut · 2011 · https://doi.org/10.1136/gut.2011.239236

• Differential expression of microRNAs in plasma of patients with colorectal cancer: a potential marker for colorectal cancer screening

  Gut · 2009 · https://doi.org/10.1136/gut.2008.167817

• Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin

  Hepatology · 2007 · https://doi.org/10.1002/hep.21668

• A second generation human haplotype map of over 3.1 million SNPs

  Nature · 2007 · https://doi.org/10.1038/nature06258

Current projects

No projects listed.