Bin Tean Teh

Research interests

Publications

• Cholangiocarcinoma

  Nature Reviews Disease Primers · 2021 · https://doi.org/10.1038/s41572-021-00300-2

• Oncogenic activation of the STAT3 pathway drives PD-L1 expression in natural killer/T-cell lymphoma

  Blood · 2018 · 10.1182/blood-2018-01-829424

• The draft genome of tropical fruit durian (Durio zibethinus)

  Nature Genetics · 2017 · https://doi.org/10.1038/ng.3972

• Whole-Genome and Epigenomic Landscapes of Etiologically Distinct Subtypes of Cholangiocarcinoma

  Cancer Discovery · 2017 · https://doi.org/10.1158/2159-8290.cd-17-0368

• Genomic and Epigenomic Profiling of High-Risk Intestinal Metaplasia Reveals Molecular Determinants of Progression to Gastric Cancer

  Cancer Cell · 2017 · https://doi.org/10.1016/j.ccell.2017.11.018

• Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia

  Science Translational Medicine · 2017 · 10.1126/scitranslmed.aan6446

• VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma

  Cancer Discovery · 2017 · https://doi.org/10.1158/2159-8290.cd-17-0375

• Gene expression signatures delineate biological and prognostic subgroups in peripheral T-cell lymphoma

  Blood · 2014 · https://doi.org/10.1182/blood-2013-11-536359

• Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

  eLife · 2014 · https://doi.org/10.7554/elife.02935

• Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancers

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2806

• Identification of Molecular Subtypes of Gastric Cancer With Different Responses to PI3-Kinase Inhibitors and 5-Fluorouracil

  Gastroenterology · 2013 · https://doi.org/10.1053/j.gastro.2013.05.010

• Exome sequencing of liver fluke–associated cholangiocarcinoma

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2273

• Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2246

• An Antioxidant Response Phenotype Shared between Hereditary and Sporadic Type 2 Papillary Renal Cell Carcinoma

  Cancer Cell · 2011 · 10.1016/j.ccr.2011.08.024

• Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

  Nature · 2011 · https://doi.org/10.1038/nature09639

• A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

  Nature · 2011 · https://doi.org/10.1038/nature10539

• Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

  Nature · 2010 · https://doi.org/10.1038/nature08672

• Interleukin-8 Mediates Resistance to Antiangiogenic Agent Sunitinib in Renal Cell Carcinoma

  Cancer Research · 2010 · 10.1158/0008-5472.can-09-3965

• Signatures of mutation and selection in the cancer genome

  Nature · 2010 · 10.1038/nature08768

• Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

  Nature Genetics · 2009 · 10.1038/ng.349

• Tubulocystic Carcinoma of the Kidney

  The American Journal of Surgical Pathology · 2008 · https://doi.org/10.1097/pas.0b013e318150df1d

• Aryl Hydrocarbon Receptor-Interacting Protein Gene Mutations in Familial Isolated Pituitary Adenomas: Analysis in 73 Families

  The Journal of Clinical Endocrinology & Metabolism · 2007 · 10.1210/jc.2006-2513

• Patterns of somatic mutation in human cancer genomes

  Nature · 2007 · https://doi.org/10.1038/nature05610

• A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer

  Nature Genetics · 2005 · https://doi.org/10.1038/ng1571

• Somatic Mutations of the Protein Kinase Gene Family in Human Lung Cancer

  Cancer Research · 2005 · https://doi.org/10.1158/0008-5472.can-05-1855

• Intragenic ERBB2 kinase mutations in tumours

  Nature · 2004 · 10.1038/431525b

• HRPT2, encoding parafibromin, is mutated in hyperparathyroidism–jaw tumor syndrome

  Nature Genetics · 2002 · https://doi.org/10.1038/ng1048

• Gene expression profiling of clear cell renal cell carcinoma: Gene identification and prognostic classification

  Proceedings of the National Academy of Sciences · 2001 · 10.1073/pnas.171209998

• Thymic Carcinoids in Multiple Endocrine Neoplasia Type 1

  Annals of Surgery · 1998 · https://doi.org/10.1097/00000658-199807000-00015

• Clustered inactivating mutations and benign polymorphisms of the calcium receptor gene in familial benign hypocalciuric hypercalcemia suggest receptor functional domains.

  The Journal of Clinical Endocrinology & Metabolism · 1996 · https://doi.org/10.1210/jcem.81.4.8636323

Current projects

No projects listed.