Stephen Baker

Research interests

Publications

• Global, regional, and national incidence and mortality burden of non-COVID-19 lower respiratory infections and aetiologies, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021

  The Lancet Infectious Diseases · 2024 · https://doi.org/10.1016/s1473-3099(24)00176-2

• Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis

  The Lancet · 2022 · https://doi.org/10.1016/s0140-6736(21)02724-0

• Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity

  Nature · 2022 · https://doi.org/10.1038/s41586-022-04474-x

• Longitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease

  Immunity · 2021 · 10.1016/j.immuni.2021.05.010

• Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03739-1

• Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

  Nature · 2021 · https://doi.org/10.1038/s41586-021-03412-7

• SARS-CoV-2 evolution during treatment of chronic infection

  Nature · 2021 · 10.1038/s41586-021-03291-y

• Drug-resistant enteric fever worldwide, 1990 to 2018: a systematic review and meta-analysis

  BMC Medicine · 2020 · 10.1186/s12916-019-1443-1

• A thermostable, closed SARS-CoV-2 spike protein trimer

  Nature Structural & Molecular Biology · 2020 · 10.1038/s41594-020-0478-5

• Genomic surveillance for hypervirulence and multi-drug resistance in invasive Klebsiella pneumoniae from South and Southeast Asia

  Genome Medicine · 2020 · 10.1186/s13073-019-0706-y

• Rapid implementation of SARS-CoV-2 sequencing to investigate cases of health-care associated COVID-19: a prospective genomic surveillance study

  The Lancet Infectious Diseases · 2020 · 10.1016/s1473-3099(20)30562-4

• Genomic insights into the emergence and spread of antimicrobial-resistant bacterial pathogens

  Science · 2018 · 10.1126/science.aar3777

• Emergence of an Extensively Drug-Resistant Salmonella enterica Serovar Typhi Clone Harboring a Promiscuous Plasmid Encoding Resistance to Fluoroquinolones and Third-Generation Cephalosporins

  mBio · 2018 · 10.1128/mbio.00105-18

• Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

  PLoS Pathogens · 2016 · 10.1371/journal.ppat.1005763

• Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae , an urgent threat to public health

  Proceedings of the National Academy of Sciences · 2015 · https://doi.org/10.1073/pnas.1501049112

• Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events

  Nature Genetics · 2015 · 10.1038/ng.3281

• Combination Antifungal Therapy for Cryptococcal Meningitis

  New England Journal of Medicine · 2013 · 10.1056/nejmoa1110404

• Rapid Pneumococcal Evolution in Response to Clinical Interventions

  Science · 2011 · 10.1126/science.1198545

• High-throughput sequencing provides insights into genome variation and evolution in Salmonella Typhi

  Nature Genetics · 2008 · 10.1038/ng.195

• The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome

  Nature Genetics · 2006 · 10.1038/ng1830

• Evolutionary History of Salmonella Typhi

  Science · 2006 · 10.1126/science.1134933

• Comparative analysis of the genome sequences of Bordetella pertussis, Bordetella parapertussis and Bordetella bronchiseptica

  Nature Genetics · 2003 · 10.1038/ng1227

• The genome sequence of Schizosaccharomyces pombe

  Nature · 2002 · https://doi.org/10.1038/nature724

• Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18

  Nature · 2001 · https://doi.org/10.1038/35101607

• Genome sequence of Yersinia pestis, the causative agent of plague

  Nature · 2001 · https://doi.org/10.1038/35097083

Current projects

No projects listed.