Chiea Chuen Khor

Research interests

Publications

• A global catalog of whole-genome diversity from 233 primate species

  Science · 2023 · https://doi.org/10.1126/science.abn7829

• Cartography of opportunistic pathogens and antibiotic resistance genes in a tertiary hospital environment

  Nature Medicine · 2020 · https://doi.org/10.1038/s41591-020-0894-4

• Identification of type 2 diabetes loci in 433,540 East Asian individuals

  Nature · 2020 · https://doi.org/10.1038/s41586-020-2263-3

• Identification of Risk Loci for Parkinson Disease in Asians and Comparison of Risk Between Asians and Europeans

  JAMA Neurology · 2020 · https://doi.org/10.1001/jamaneurol.2020.0428

• Large-Scale Whole-Genome Sequencing of Three Diverse Asian Populations in Singapore

  Cell · 2019 · https://doi.org/10.1016/j.cell.2019.09.019

• Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network

  Cell stem cell · 2019 · https://doi.org/10.1016/j.stem.2019.06.009

• Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria

  Nature Communications · 2019 · https://doi.org/10.1038/s41467-019-11576-0

• Frequent transmission of the Mycobacterium tuberculosis Beijing lineage and positive selection for the EsxW Beijing variant in Vietnam

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0117-9

• Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

  PLoS Medicine · 2017 · https://doi.org/10.1371/journal.pmed.1002383

• New insights into the genetics of primary open-angle glaucoma based on meta-analyses of intraocular pressure and optic disc characteristics.

  Human Molecular Genetics · 2016 · https://doi.org/10.1093/hmg/ddw399

• Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma

  Nature Genetics · 2016 · https://doi.org/10.1038/ng.3540

• Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma

  Nature Genetics · 2016 · https://doi.org/10.1038/ng.3482

• Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

  Nature Genetics · 2015 · https://doi.org/10.1038/ng.3405

• Cloning and variation of ground state intestinal stem cells

  Nature · 2015 · https://doi.org/10.1038/nature14484

• Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

  Nature Communications · 2015 · https://doi.org/10.1038/ncomms6897

• Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma

  Nature Genetics · 2014 · https://doi.org/10.1038/ng.3078

• Genome-wide analysis of multi-ancestry cohorts identifies new loci influencing intraocular pressure and susceptibility to glaucoma

  Nature Genetics · 2014 · https://doi.org/10.1038/ng.3087

• Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2554

• Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus

  Nature Genetics · 2013 · https://doi.org/10.1038/ng.2506

• High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2462

• Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2390

• Genome-Wide Expression Profiling Identifies Type 1 Interferon Response Pathways in Active Tuberculosis

  PLoS ONE · 2012 · https://doi.org/10.1371/journal.pone.0045839

• LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets

  Nucleic Acids Research · 2012 · https://doi.org/10.1093/nar/gks918

• Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1

  Nature Genetics · 2011 · https://doi.org/10.1038/ng.960

• Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease

  Nature Genetics · 2011 · https://doi.org/10.1038/ng.981

• Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

  Nature Genetics · 2011 · https://doi.org/10.1038/ng.921

• Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.640

• A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis

  Nature Genetics · 2007 · https://doi.org/10.1038/ng1976

Current projects

No projects listed.