Anis Larbi

Research interests

Publications

• Immunology of Aging: the Birth of Inflammaging

  Clinical Reviews in Allergy & Immunology · 2021 · https://doi.org/10.1007/s12016-021-08899-6

• Combinatorial Single-Cell Analyses of Granulocyte-Monocyte Progenitor Heterogeneity Reveals an Early Uni-potent Neutrophil Progenitor

  Immunity · 2020 · https://doi.org/10.1016/j.immuni.2020.06.005

• RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types

  Cell Reports · 2019 · https://doi.org/10.1016/j.celrep.2019.01.041

• Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

  Science · 2019 · https://doi.org/10.1126/science.aau0964

• Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates

  Nature · 2018 · https://doi.org/10.1038/s41586-018-0130-2

• Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions

  Immunity · 2018 · https://doi.org/10.1016/j.immuni.2018.02.002

• Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes?

  Frontiers in Immunology · 2018 · https://doi.org/10.3389/fimmu.2017.01960

• The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence

  Cell Death and Disease · 2018 · https://doi.org/10.1038/s41419-018-0327-1

• Can an Infection Hypothesis Explain the Beta Amyloid Hypothesis of Alzheimer’s Disease?

  Frontiers in Aging Neuroscience · 2018 · https://doi.org/10.3389/fnagi.2018.00224

• Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner

  Cell · 2017 · 10.1016/j.cell.2017.11.042

• Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2

  Nature · 2017 · https://doi.org/10.1038/nature22795

• Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function

  Immunity · 2017 · https://doi.org/10.1016/j.immuni.2017.06.017

• CD57 in human natural killer cells and T-lymphocytes

  Cancer Immunology Immunotherapy · 2016 · https://doi.org/10.1007/s00262-016-1803-z

• Unsupervised High-Dimensional Analysis Aligns Dendritic Cells across Tissues and Species

  Immunity · 2016 · 10.1016/j.immuni.2016.08.015

• CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses

  The Journal of Experimental Medicine · 2016 · https://doi.org/10.1084/jem.20160800

• C-Myb+ Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tissue-Resident Macrophages

  Immunity · 2015 · https://doi.org/10.1016/j.immuni.2015.03.011

• Frailty in Older Persons: Multisystem Risk Factors and the Frailty Risk Index (FRI)

  Journal of the American Medical Directors Association · 2014 · https://doi.org/10.1016/j.jamda.2014.03.008

• Neutrophil mobilization via plerixafor-mediated CXCR4 inhibition arises from lung demargination and blockade of neutrophil homing to the bone marrow

  The Journal of Experimental Medicine · 2013 · https://doi.org/10.1084/jem.20130056

• Human Tissues Contain CD141hi Cross-Presenting Dendritic Cells with Functional Homology to Mouse CD103+ Nonlymphoid Dendritic Cells

  Immunity · 2012 · 10.1016/j.immuni.2012.04.012

• CMV and Immunosenescence: from basics to clinics

  Immunity & Ageing · 2012 · https://doi.org/10.1186/1742-4933-9-23

• Aging, frailty and age-related diseases

  Biogerontology · 2010 · https://doi.org/10.1007/s10522-010-9287-2

• Biomarkers of human immunosenescence: impact of Cytomegalovirus infection

  Current Opinion in Immunology · 2009 · https://doi.org/10.1016/j.coi.2009.05.012

• Dramatic Shifts in Circulating CD4 but not CD8 T Cell Subsets in Mild Alzheimer's Disease

  Journal of Alzheimer s Disease · 2009 · https://doi.org/10.3233/jad-2009-1015

• Aging of the Immune System as a Prognostic Factor for Human Longevity

  Physiology · 2008 · https://doi.org/10.1152/physiol.00040.2007

• Multiparameter flow cytometric analysis of CD4 and CD8 T cell subsets in young and old people

  Immunity & Ageing · 2008 · https://doi.org/10.1186/1742-4933-5-6

• Cytomegalovirus and human immunosenescence

  Reviews in Medical Virology · 2008 · https://doi.org/10.1002/rmv.598

• Cytomegalovirus Infection

  Annals of the New York Academy of Sciences · 2007 · https://doi.org/10.1196/annals.1396.043

Current projects

No projects listed.