Yukun Zhang

Research interests

Publications

• The role of oxidative stress in intervertebral disc degeneration: Mechanisms and therapeutic implications

  Ageing Research Reviews · 2024 · https://doi.org/10.1016/j.arr.2024.102323

• WTAP-mediated m6A modification of lncRNA NORAD promotes intervertebral disc degeneration

  Nature Communications · 2022 · https://doi.org/10.1038/s41467-022-28990-6

• Cytosolic escape of mitochondrial DNA triggers cGAS-STING-NLRP3 axis-dependent nucleus pulposus cell pyroptosis

  Experimental & Molecular Medicine · 2022 · https://doi.org/10.1038/s12276-022-00729-9

• Metformin facilitates mesenchymal stem cell-derived extracellular nanovesicles release and optimizes therapeutic efficacy in intervertebral disc degeneration

  Biomaterials · 2021 · https://doi.org/10.1016/j.biomaterials.2021.120850

• Ferroportin‐Dependent Iron Homeostasis Protects against Oxidative Stress‐Induced Nucleus Pulposus Cell Ferroptosis and Ameliorates Intervertebral Disc Degeneration In Vivo

  Oxidative Medicine and Cellular Longevity · 2021 · https://doi.org/10.1155/2021/6670497

• Mechanosensitive Ion Channel Piezo1 Activated by Matrix Stiffness Regulates Oxidative Stress‐Induced Senescence and Apoptosis in Human Intervertebral Disc Degeneration

  Oxidative Medicine and Cellular Longevity · 2021 · https://doi.org/10.1155/2021/8884922

• CircRNA-CIDN mitigated compression loading-induced damage in human nucleus pulposus cells via miR-34a-5p/SIRT1 axis

  EBioMedicine · 2020 · https://doi.org/10.1016/j.ebiom.2020.102679

• Acid‐sensing ion channels regulate nucleus pulposus cell inflammation and pyroptosis via the NLRP3 inflammasome in intervertebral disc degeneration

  Cell Proliferation · 2020 · https://doi.org/10.1111/cpr.12941

• Traditional Chinese medicine combined with pulmonary drug delivery system and idiopathic pulmonary fibrosis: Rationale and therapeutic potential

  Biomedicine & Pharmacotherapy · 2020 · https://doi.org/10.1016/j.biopha.2020.111072

• Restoration of Autophagic Flux Rescues Oxidative Damage and Mitochondrial Dysfunction to Protect against Intervertebral Disc Degeneration

  Oxidative Medicine and Cellular Longevity · 2019 · https://doi.org/10.1155/2019/7810320

• Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo

  Theranostics · 2019 · https://doi.org/10.7150/thno.33638

• Dysbiosis of the Gut Microbiome in Lung Cancer

  Frontiers in Cellular and Infection Microbiology · 2019 · https://doi.org/10.3389/fcimb.2019.00112

• Sirtuin 3-dependent mitochondrial redox homeostasis protects against AGEs-induced intervertebral disc degeneration

  Redox Biology · 2018 · https://doi.org/10.1016/j.redox.2018.09.006

• Advanced glycation end products regulate anabolic and catabolic activities via NLRP3‐inflammasome activation in human nucleus pulposus cells

  Journal of Cellular and Molecular Medicine · 2017 · https://doi.org/10.1111/jcmm.13067

• Effects of Sleep Quality on the Association between Problematic Mobile Phone Use and Mental Health Symptoms in Chinese College Students

  International Journal of Environmental Research and Public Health · 2017 · https://doi.org/10.3390/ijerph14020185

• Analysis of Workflow and Time to Treatment on Thrombectomy Outcome in the Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke (ESCAPE) Randomized, Controlled Trial

  Circulation · 2016 · https://doi.org/10.1161/circulationaha.115.019983

• Low Physical Activity and High Screen Time Can Increase the Risks of Mental Health Problems and Poor Sleep Quality among Chinese College Students

  PLoS ONE · 2015 · https://doi.org/10.1371/journal.pone.0119607

• MicroRNA-21 controls the development of osteoarthritis by targeting GDF-5 in chondrocytes

  Experimental & Molecular Medicine · 2014 · https://doi.org/10.1038/emm.2013.152

Current projects

No projects listed.