Stephen Friend

Research interests

Publications

• The mPower study, Parkinson disease mobile data collected using ResearchKit

  Scientific Data · 2016 · https://doi.org/10.1038/sdata.2016.11

• Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data

  The Lancet Oncology · 2016 · https://doi.org/10.1016/s1470-2045(16)30560-5

• Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open clinical trial data

  The Lancet Oncology · 2016 · https://doi.org/10.1016/s1470-2045(16)30560-5

• Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection

  Nature Methods · 2015 · https://doi.org/10.1038/nmeth.3407

• The consensus molecular subtypes of colorectal cancer

  Nature Medicine · 2015 · https://doi.org/10.1038/nm.3967

• Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

  Molecular Cell · 2012 · https://doi.org/10.1016/j.molcel.2012.10.016

• Predictive, personalized, preventive, participatory (P4) cancer medicine

  Nature Reviews Clinical Oncology · 2011 · https://doi.org/10.1038/nrclinonc.2010.227

• Genetics of gene expression surveyed in maize, mouse and man

  Nature · 2003 · https://doi.org/10.1038/nature01434

• Gene expression profiling predicts clinical outcome of breast cancer

  Nature · 2002 · https://doi.org/10.1038/415530a

• A Gene-Expression Signature as a Predictor of Survival in Breast Cancer

  New England Journal of Medicine · 2002 · https://doi.org/10.1056/nejmoa021967

• Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer

  Nature Biotechnology · 2001 · https://doi.org/10.1038/86730

• Signaling and Circuitry of Multiple MAPK Pathways Revealed by a Matrix of Global Gene Expression Profiles

  Science · 2000 · https://doi.org/10.1126/science.287.5454.873

• Functional Discovery via a Compendium of Expression Profiles

  Cell · 2000 · https://doi.org/10.1016/s0092-8674(00)00015-5

• Functional Characterization of the S. cerevisiae Genome by Gene Deletion and Parallel Analysis

  Science · 1999 · https://doi.org/10.1126/science.285.5429.901

• Drug target validation and identification of secondary drug target effects using DNA microarrays

  Nature Medicine · 1998 · https://doi.org/10.1038/3282

• Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents.

  PubMed · 1997

• Integrating Genetic Approaches into the Discovery of Anticancer Drugs

  Science · 1997 · https://doi.org/10.1126/science.278.5340.1064

• An Information-Intensive Approach to the Molecular Pharmacology of Cancer

  Science · 1997 · 10.1126/science.275.5298.343

• Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms

  Science · 1990 · https://doi.org/10.1126/science.1978757

• Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

  Nature · 1988 · https://doi.org/10.1038/334124a0

• A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

  Nature · 1986 · 10.1038/323643a0

Current projects

No projects listed.