Fengtang Yang

Research interests

Publications

• Establishment of porcine and human expanded potential stem cells

  Nature Cell Biology · 2019 · 10.1038/s41556-019-0333-2

• Human blood vessel organoids as a model of diabetic vasculopathy

  Nature · 2019 · https://doi.org/10.1038/s41586-018-0858-8

• ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks

  Nature Communications · 2019 · 10.1038/s41467-018-07729-2

• Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

  Nature Cell Biology · 2018 · 10.1038/s41556-018-0140-1

• Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci

  Nature Genetics · 2018 · 10.1038/s41588-018-0223-8

• Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes

  Nature · 2018 · 10.1038/nature25459

• Establishment of mouse expanded potential stem cells

  Nature · 2017 · 10.1038/nature24052

• Formin Is Associated with Left-Right Asymmetry in the Pond Snail and the Frog

  Current Biology · 2016 · 10.1016/j.cub.2015.12.071

• Punctuated bursts in human male demography inferred from 1,244 worldwide Y-chromosome sequences

  Nature Genetics · 2016 · 10.1038/ng.3559

• Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

  Genome Research · 2015 · 10.1101/gr.190470.115

• TEX11 is mutated in infertile men with azoospermia and regulates genome‐wide recombination rates in mouse

  EMBO Molecular Medicine · 2015 · 10.15252/emmm.201404967

• CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional cancer genomics in mice

  Proceedings of the National Academy of Sciences · 2015 · 10.1073/pnas.1512392112

• Transmissible Dog Cancer Genome Reveals the Origin and History of an Ancient Cell Lineage

  Science · 2014 · 10.1126/science.1247167

• A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer

  Nature Medicine · 2014 · 10.1038/nm.3646

• Genome Sequencing and Analysis of the Tasmanian Devil and Its Transmissible Cancer

  Cell · 2012 · 10.1016/j.cell.2011.11.065

• Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

  Cell · 2011 · https://doi.org/10.1016/j.cell.2010.11.055

• Signatures of mutation and selection in the cancer genome

  Nature · 2010 · https://doi.org/10.1038/nature08768

• PiggyBac Transposon Mutagenesis: A Tool for Cancer Gene Discovery in Mice

  Science · 2010 · 10.1126/science.1193004

• Genetic engineering of human stem cells for enhanced angiogenesis using biodegradable polymeric nanoparticles

  Proceedings of the National Academy of Sciences · 2009 · 10.1073/pnas.0905432106

• Copy number variation and evolution in humans and chimpanzees

  Genome Research · 2008 · 10.1101/gr.082016.108

• Paired-End Mapping Reveals Extensive Structural Variation in the Human Genome

  Science · 2007 · https://doi.org/10.1126/science.1149504

• Global variation in copy number in the human genome

  Nature · 2006 · https://doi.org/10.1038/nature05329

• An abundance of X-linked genes expressed in spermatogonia

  Nature Genetics · 2001 · 10.1038/86927

• Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues

  Journal of Cell Science · 2001 · 10.1242/jcs.114.24.4485

• A Complete Comparative Chromosome Map for the Dog, Red Fox, and Human and Its Integration with Canine Genetic Maps

  Genomics · 1999 · 10.1006/geno.1999.5989

Current projects

No projects listed.