Manuel Serrano

Research interests

Publications

• Hallmarks of aging: An expanding universe

  Cell · 2023 · https://doi.org/10.1016/j.cell.2022.11.001

• Cellular Senescence Is Immunogenic and Promotes Antitumor Immunity

  Cancer Discovery · 2022 · https://doi.org/10.1158/2159-8290.cd-22-0523

• Restoration of energy homeostasis by SIRT6 extends healthy lifespan

  Nature Communications · 2021 · https://doi.org/10.1038/s41467-021-23545-7

• Cellular Senescence: Defining a Path Forward

  Cell · 2019 · https://doi.org/10.1016/j.cell.2019.10.005

• The Hallmarks of Aging

  Cell · 2013 · https://doi.org/10.1016/j.cell.2013.05.039

• Oncogenicity of the Developmental Transcription Factor Sox9

  Cancer Research · 2012 · https://doi.org/10.1158/0008-5472.can-11-3660

• Cellular Senescence in Cancer and Aging

  Cell · 2007 · https://doi.org/10.1016/j.cell.2007.07.003

• Senescence in premalignant tumours

  Nature · 2005 · https://doi.org/10.1038/436642a

• Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d

  Nature · 1998 · https://doi.org/10.1038/26164

• Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

  Cell · 1997 · https://doi.org/10.1016/s0092-8674(00)81902-9

• A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

  Nature · 1993 · https://doi.org/10.1038/366704a0

Current projects

No projects listed.