Shahab Uddin

Research interests

Publications

• Cancer cell plasticity: from cellular, molecular, and genetic mechanisms to tumor heterogeneity and drug resistance

  Cancer and Metastasis Reviews · 2024 · 10.1007/s10555-024-10172-z

• H2AX: A key player in DNA damage response and a promising target for cancer therapy

  Biomedicine & Pharmacotherapy · 2024 · https://doi.org/10.1016/j.biopha.2024.116663

• Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments

  Journal of Translational Medicine · 2023 · 10.1186/s12967-023-04292-3

• CAR-cell therapy in the era of solid tumor treatment: current challenges and emerging therapeutic advances

  Molecular Cancer · 2023 · https://doi.org/10.1186/s12943-023-01723-z

• Targeting cancer signaling pathways by natural products: Exploring promising anti-cancer agents

  Biomedicine & Pharmacotherapy · 2022 · 10.1016/j.biopha.2022.113054

• Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics and vaccines

  Annals of Medicine · 2022 · 10.1080/07853890.2022.2031274

• Dynamic liquid biopsy components as predictive and prognostic biomarkers in colorectal cancer

  Journal of Experimental & Clinical Cancer Research · 2022 · https://doi.org/10.1186/s13046-022-02318-0

• Cytokine‐ and chemokine‐induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy

  癌症：英文版 · 2022 · 10.1002/cac2.12295

• Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance

  Molecular Cancer · 2020 · 10.1186/s12943-020-01175-9

• Inducing Angiogenesis, a Key Step in Cancer Vascularization, and Treatment Approaches

  Cancers · 2020 · 10.3390/cancers12051172

• Tight Junction Proteins and Signaling Pathways in Cancer and Inflammation: A Functional Crosstalk

  Frontiers in Physiology · 2019 · 10.3389/fphys.2018.01942

• Extracellular vesicles-mediated intercellular communication: roles in the tumor microenvironment and anti-cancer drug resistance

  Molecular Cancer · 2019 · 10.1186/s12943-019-0965-7

• Role of miRNA-Regulated Cancer Stem Cells in the Pathogenesis of Human Malignancies

  Cells · 2019 · 10.3390/cells8080840

• Cisplatin based therapy: the role of the mitogen activated protein kinase signaling pathway

  Journal of Translational Medicine · 2018 · 10.1186/s12967-018-1471-1

• RAS-mediated oncogenic signaling pathways in human malignancies

  Seminars in Cancer Biology · 2018 · 10.1016/j.semcancer.2018.03.001

• Vascular Endothelial Growth Factor (VEGF) Signaling in Tumour Vascularization: Potential and Challenges

  Current Vascular Pharmacology · 2017 · 10.2174/1570161115666170105124038

• Targeting acute myeloid leukemia stem cell signaling by natural products

  Molecular Cancer · 2017 · 10.1186/s12943-016-0571-x

• Clinicopathological Analysis of Papillary Thyroid Cancer withPIK3CAAlterations in a Middle Eastern Population

  The Journal of Clinical Endocrinology & Metabolism · 2007 · 10.1210/jc.2007-1717

• Curcumin induces apoptosis via inhibition of PI3′-kinase/AKT pathway in Acute T cell Leukemias

  APOPTOSIS · 2006 · 10.1007/s10495-006-3392-3

• Role of phosphatidylinositol 3′-kinase/AKT pathway in diffuse large B-cell lymphoma survival

  Blood · 2006 · 10.1182/blood-2006-04-016907

• Protein Kinase C-δ (PKC-δ) Is Activated by Type I Interferons and Mediates Phosphorylation of Stat1 on Serine 727

  Journal of Biological Chemistry · 2002 · 10.1074/jbc.m109671200

• Protein Kinase C-δ Regulates Thrombin-Induced ICAM-1 Gene Expression in Endothelial Cells via Activation of p38 Mitogen-Activated Protein Kinase

  Molecular and Cellular Biology · 2001 · 10.1128/mcb.21.16.5554-5565.2001

• The Rac1/p38 Mitogen-activated Protein Kinase Pathway Is Required for Interferon α-dependent Transcriptional Activation but Not Serine Phosphorylation of Stat Proteins

  Journal of Biological Chemistry · 2000 · 10.1074/jbc.m003170200

• Activation of the p38 Mitogen-activated Protein Kinase by Type I Interferons

  Journal of Biological Chemistry · 1999 · 10.1074/jbc.274.42.30127

• Interferon-α Resistance in a Cutaneous T-Cell Lymphoma Cell Line Is Associated With Lack of STAT1 Expression

  Blood · 1998 · 10.1182/blood.v91.2.570

• Interferon-α Engages the Insulin Receptor Substrate-1 to Associate with the Phosphatidylinositol 3′-Kinase

  Journal of Biological Chemistry · 1995 · 10.1074/jbc.270.27.15938

Current projects

No projects listed.