Egbert F. Smit

Research interests

Publications

• Oncogene-addicted metastatic non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

  Annals of Oncology · 2023 · https://doi.org/10.1016/j.annonc.2022.12.009

• Non-oncogene-addicted metastatic non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

  Annals of Oncology · 2023 · https://doi.org/10.1016/j.annonc.2022.12.013

• Trastuzumab Deruxtecan in HER2 -Mutant Non–Small-Cell Lung Cancer

  New England Journal of Medicine · 2021 · https://doi.org/10.1056/nejmoa2112431

• Capmatinib in MET Exon 14–Mutated or MET -Amplified Non–Small-Cell Lung Cancer

  New England Journal of Medicine · 2020 · https://doi.org/10.1056/nejmoa2002787

• Tepotinib in Non–Small-Cell Lung Cancer with MET Exon 14 Skipping Mutations

  New England Journal of Medicine · 2020 · https://doi.org/10.1056/nejmoa2004407

• Long‐term expanding human airway organoids for disease modeling

  The EMBO Journal · 2019 · 10.15252/embj.2018100300

• Pan-cancer whole-genome analyses of metastatic solid tumours

  Nature · 2019 · 10.1038/s41586-019-1689-y

• Predicting response to cancer immunotherapy using noninvasive radiomic biomarkers

  Annals of Oncology · 2019 · 10.1093/annonc/mdz108

• Whole body PD-1 and PD-L1 positron emission tomography in patients with non-small-cell lung cancer

  Nature Communications · 2018 · 10.1038/s41467-018-07131-y

• Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids

  Cell · 2018 · 10.1016/j.cell.2018.07.009

• Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

  Annals of Oncology · 2018 · https://doi.org/10.1093/annonc/mdy275

• Dabrafenib plus trametinib in patients with previously untreated BRAFV600E-mutant metastatic non-small-cell lung cancer: an open-label, phase 2 trial

  The Lancet Oncology · 2017 · https://doi.org/10.1016/s1470-2045(17)30679-4

• Brigatinib in Patients With Crizotinib-Refractory Anaplastic Lymphoma Kinase–Positive Non–Small-Cell Lung Cancer: A Randomized, Multicenter Phase II Trial

  Journal of Clinical Oncology · 2017 · 10.1200/jco.2016.71.5904

• Dabrafenib in patients with BRAFV600E-positive advanced non-small-cell lung cancer: a single-arm, multicentre, open-label, phase 2 trial

  The Lancet Oncology · 2016 · 10.1016/s1470-2045(16)00077-2

• A randomized phase II study of the MEK1/MEK2 inhibitor trametinib (GSK1120212) compared with docetaxel in KRAS-mutant advanced non-small-cell lung cancer (NSCLC)

  Annals of Oncology · 2015 · 10.1093/annonc/mdv072

• Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials

  The Lancet Oncology · 2015 · https://doi.org/10.1016/s1470-2045(15)70168-3

• RNA-Seq of Tumor-Educated Platelets Enables Blood-Based Pan-Cancer, Multiclass, and Molecular Pathway Cancer Diagnostics

  Cancer Cell · 2015 · 10.1016/j.ccell.2015.09.018

• 2nd ESMO Consensus Conference on Lung Cancer: early-stage non-small-cell lung cancer consensus on diagnosis, treatment and follow-up

  Annals of Oncology · 2014 · 10.1093/annonc/mdu089

• Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

  Nature Genetics · 2012 · https://doi.org/10.1038/ng.2396

• Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer

  Science Translational Medicine · 2010 · 10.1126/scitranslmed.3001451

• Outcomes of Risk-Adapted Fractionated Stereotactic Radiotherapy for Stage I Non–Small-Cell Lung Cancer

  International Journal of Radiation Oncology*Biology*Physics · 2008 · 10.1016/j.ijrobp.2007.10.053

• Randomized Controlled Trial of Resection Versus Radiotherapy After Induction Chemotherapy in Stage IIIA-N2 Non-Small-Cell Lung Cancer

  JNCI Journal of the National Cancer Institute · 2007 · 10.1093/jnci/djk093

• Clinical Prediction Model To Characterize Pulmonary Nodules

  CHEST Journal · 2005 · 10.1378/chest.128.4.2490

• Multi-Institutional Randomized Phase II Trial of Gefitinib for Previously Treated Patients With Advanced Non–Small-Cell Lung Cancer

  Journal of Clinical Oncology · 2003 · https://doi.org/10.1200/jco.2003.10.038

• Effectiveness of positron emission tomography in the preoperative assessment of patients with suspected non-small-cell lung cancer: the PLUS multicentre randomised trial

  The Lancet · 2002 · 10.1016/s0140-6736(02)08352-6

Current projects

No projects listed.