Martin Ingelsson

Research interests

Publications

• Crosstalk between astrocytes and microglia results in increased degradation of α-synuclein and amyloid-β aggregates

  Journal of Neuroinflammation · 2021 · 10.1186/s12974-021-02158-3

• α-Synuclein strains target distinct brain regions and cell types

  Nature Neuroscience · 2019 · 10.1038/s41593-019-0541-x

• Genetic predisposition to mosaic Y chromosome loss in blood

  Nature · 2019 · 10.1038/s41586-019-1765-3

• High levels of AAV vector integration into CRISPR-induced DNA breaks

  Nature Communications · 2019 · 10.1038/s41467-019-12449-2

• Application of non-HDL cholesterol for population-based cardiovascular risk stratification: results from the Multinational Cardiovascular Risk Consortium

  The Lancet · 2019 · 10.1016/s0140-6736(19)32519-x

• Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

  Nature Genetics · 2018 · https://doi.org/10.1038/s41588-018-0241-6

• Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomers

  Acta Neuropathologica · 2018 · 10.1007/s00401-018-1868-1

• Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes

  Journal of Neuroscience · 2017 · 10.1523/jneurosci.0983-17.2017

• Extensive uptake of α-synuclein oligomers in astrocytes results in sustained intracellular deposits and mitochondrial damage

  Molecular and Cellular Neuroscience · 2017 · 10.1016/j.mcn.2017.04.009

• Consensus guidelines for lumbar puncture in patients with neurological diseases

  Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · 2017 · 10.1016/j.dadm.2017.04.007

• Mosaic Loss of Chromosome Y in Blood Is Associated with Alzheimer Disease

  The American Journal of Human Genetics · 2016 · 10.1016/j.ajhg.2016.05.014

• Alpha-Synuclein Oligomers—Neurotoxic Molecules in Parkinson's Disease and Other Lewy Body Disorders

  Frontiers in Neuroscience · 2016 · 10.3389/fnins.2016.00408

• In Vivo Seeding and Cross-Seeding of Localized Amyloidosis

  American Journal Of Pathology · 2015 · 10.1016/j.ajpath.2014.11.016

• Performance and complications of lumbar puncture in memory clinics: Results of the multicenter lumbar puncture feasibility study

  Alzheimer s & Dementia · 2015 · 10.1016/j.jalz.2015.08.003

• Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease

  Alzheimer s & Dementia · 2014 · 10.1016/j.jalz.2014.10.009

• Smoking is associated with mosaic loss of chromosome Y

  Science · 2014 · 10.1126/science.1262092

• Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients

  Proceedings of the National Academy of Sciences · 2014 · 10.1073/pnas.1408900111

• Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease

  Molecular Psychiatry · 2012 · https://doi.org/10.1038/mp.2012.14

• Extracellular Alpha-Synuclein Oligomers Modulate Synaptic Transmission and Impair LTP Via NMDA-Receptor Activation

  Journal of Neuroscience · 2012 · 10.1523/jneurosci.0234-12.2012

• PBT2 Rapidly Improves Cognition in Alzheimer's Disease: Additional Phase II Analyses

  Journal of Alzheimer s Disease · 2010 · 10.3233/jad-2010-1390

• The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide

  PLoS ONE · 2010 · https://doi.org/10.1371/journal.pone.0009505

• Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function

  Science · 2005 · https://doi.org/10.1126/science.1113694

• Family-Based Association between Alzheimer's Disease and Variants inUBQLN1

  New England Journal of Medicine · 2005 · 10.1056/nejmoa042765

• Early Aβ accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain

  Neurology · 2004 · 10.1212/01.wnl.0000115115.98960.37

• Uniform polarity microtubule assemblies imaged in native brain tissue by second-harmonic generation microscopy

  Proceedings of the National Academy of Sciences · 2003 · 10.1073/pnas.0731953100

Current projects

No projects listed.