Lena Claesson‐Welsh

Research interests

Publications

• Permeability of the Endothelial Barrier: Identifying and Reconciling Controversies

  Trends in Molecular Medicine · 2020 · https://doi.org/10.1016/j.molmed.2020.11.006

• Mechanisms and regulation of endothelial VEGF receptor signalling

  Nature Reviews Molecular Cell Biology · 2016 · https://doi.org/10.1038/nrm.2016.87

• VEGFA and tumour angiogenesis

  Journal of Internal Medicine · 2013 · 10.1111/joim.12019

• Signal Transduction by Vascular Endothelial Growth Factor Receptors

  Cold Spring Harbor Perspectives in Medicine · 2012 · 10.1101/cshperspect.a006502

• Signal transduction by vascular endothelial growth factor receptors

  Biochemical Journal · 2011 · 10.1042/bj20110301

• HRG Inhibits Tumor Growth and Metastasis by Inducing Macrophage Polarization and Vessel Normalization through Downregulation of PlGF

  Cancer Cell · 2011 · https://doi.org/10.1016/j.ccr.2010.11.009

• Vascular endothelial growth factor B controls endothelial fatty acid uptake

  Nature · 2010 · 10.1038/nature08945

• VEGF receptor signalling ? in control of vascular function

  Nature Reviews Molecular Cell Biology · 2006 · https://doi.org/10.1038/nrm1911

• Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis

  Experimental Cell Research · 2005 · https://doi.org/10.1016/j.yexcr.2005.11.012

• A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2

  Nature Medicine · 2003 · 10.1038/nm846

• VEGF-receptor signal transduction

  Trends in Biochemical Sciences · 2003 · 10.1016/s0968-0004(03)00193-2

• FGF and VEGF function in angiogenesis: signalling pathways, biological responses and therapeutic inhibition

  Trends in Pharmacological Sciences · 2001 · https://doi.org/10.1016/s0165-6147(00)01676-x

• VEGF Receptor Signal Transduction

  Science s STKE · 2001 · 10.1126/stke.2001.112.re21

• Regulation of angiogenesis via vascular endothelial growth factor receptors.

  PubMed · 2000

• Vascular endothelial growth factor C induces angiogenesis in vivo

  Proceedings of the National Academy of Sciences · 1998 · 10.1073/pnas.95.24.14389

• 2′-Fluoropyrimidine RNA-based Aptamers to the 165-Amino Acid Form of Vascular Endothelial Growth Factor (VEGF165)

  Journal of Biological Chemistry · 1998 · 10.1074/jbc.273.32.20556

• Proteolytic processing regulates receptor specificity and activity of VEGF‐C

  The EMBO Journal · 1997 · 10.1093/emboj/16.13.3898

• PDGF stimulates an increase in GTP–Rac via activation of phosphoinositide 3-kinase

  Current Biology · 1995 · 10.1016/s0960-9822(95)00080-7

• Platelet-derived growth factor receptor signals.

  Journal of Biological Chemistry · 1994 · 10.1016/s0021-9258(18)31591-6

• Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor.

  Journal of Biological Chemistry · 1994 · https://doi.org/10.1016/s0021-9258(18)47116-5

• Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling

  Current Biology · 1994 · 10.1016/s0960-9822(00)00087-7

• Platelet-derived growth factor and its receptors in human glioma tissue: expression of messenger RNA and protein suggests the presence of autocrine and paracrine loops.

  PubMed · 1992

• FGFR‐4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern.

  The EMBO Journal · 1991 · 10.1002/j.1460-2075.1991.tb07654.x

• TGF-β1 binding protein: A component of the large latent complex of TGF-β1 with multiple repeat sequences

  Cell · 1990 · 10.1016/0092-8674(90)90069-q

• cDNA cloning and expression of the human A-type platelet-derived growth factor (PDGF) receptor establishes structural similarity to the B-type PDGF receptor.

  Proceedings of the National Academy of Sciences · 1989 · 10.1073/pnas.86.13.4917

Current projects

No projects listed.