Christer Betsholtz

Research interests

Publications

• Microvascular stabilization via blood-brain barrier regulation prevents seizure activity

  Nature Communications · 2022 · https://doi.org/10.1038/s41467-022-29657-y

• Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease

  Journal of the American College of Cardiology · 2017 · https://doi.org/10.1016/j.jacc.2016.11.056

• Meta-Analysis of Genome-Wide Association Studies for Abdominal Aortic Aneurysm Identifies Four New Disease-Specific Risk Loci

  Circulation Research · 2016 · https://doi.org/10.1161/circresaha.116.308765

• Age-dependent modulation of vascular niches for haematopoietic stem cells

  Nature · 2016 · https://doi.org/10.1038/nature17638

• Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq

  Science · 2015 · https://doi.org/10.1126/science.aaa1934

• Apolipoprotein E controls cerebrovascular integrity via cyclophilin A

  Nature · 2012 · https://doi.org/10.1038/nature11087

• Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises

  Developmental Cell · 2011 · https://doi.org/10.1016/j.devcel.2011.07.001

• Pericytes regulate the blood–brain barrier

  Nature · 2010 · https://doi.org/10.1038/nature09522

• Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

  Nature · 2008 · https://doi.org/10.1038/nature07083

• Role of platelet-derived growth factors in physiology and medicine

  Genes & Development · 2008 · https://doi.org/10.1101/gad.1653708

• Large‐scale identification of genes implicated in kidney glomerulus development and function

  The EMBO Journal · 2006 · https://doi.org/10.1038/sj.emboj.7601014

• Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling

  Developmental Biology · 2003 · https://doi.org/10.1016/s0012-1606(03)00356-7

• Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins

  Nature Immunology · 2003 · 10.1038/ni1013

• VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia

  The Journal of Cell Biology · 2003 · https://doi.org/10.1083/jcb.200302047

• Vascular Endothelial Growth Factor-B–Deficient Mice Display an Atrial Conduction Defect

  Circulation · 2001 · https://doi.org/10.1161/01.cir.104.3.358

• Defective oligodendrocyte development and severe hypomyelination in PDGF-A knockout mice

  Development · 1999 · https://doi.org/10.1242/dev.126.3.457

• Abnormal Reaction to Central Nervous System Injury in Mice Lacking Glial Fibrillary Acidic Protein and Vimentin

  The Journal of Cell Biology · 1999 · https://doi.org/10.1083/jcb.145.3.503

• Oligodendrocyte Population Dynamics and the Role of PDGF In Vivo

  Neuron · 1998 · https://doi.org/10.1016/s0896-6273(00)80469-9

• Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities.

  Genes & Development · 1994 · https://doi.org/10.1101/gad.8.16.1875

Current projects

No projects listed.