Eric J. Topol

Research interests

Publications

• Generative artificial intelligence and ethical considerations in health care: a scoping review and ethics checklist

  The Lancet Digital Health · 2024 · https://doi.org/10.1016/s2589-7500(24)00143-2

• Transforming Cardiovascular Care With Artificial Intelligence: From Discovery to Practice

  Journal of the American College of Cardiology · 2024 · https://doi.org/10.1016/j.jacc.2024.05.003

• A foundation model for generalizable disease detection from retinal images

  Nature · 2023 · https://doi.org/10.1038/s41586-023-06555-x

• Long COVID: major findings, mechanisms and recommendations

  Nature Reviews Microbiology · 2023 · https://doi.org/10.1038/s41579-022-00846-2

• Foundation models for generalist medical artificial intelligence

  Nature · 2023 · https://doi.org/10.1038/s41586-023-05881-4

• Multimodal biomedical AI

  Nature Medicine · 2022 · 10.1038/s41591-022-01981-2

• AI in health and medicine

  Nature Medicine · 2022 · https://doi.org/10.1038/s41591-021-01614-0

• The Promise of Digital Health: Then, Now, and the Future

  NAM Perspectives · 2022 · https://doi.org/10.31478/202206e

• The All of Us Research Program: Data quality, utility, and diversity

  Patterns · 2022 · https://doi.org/10.1016/j.patter.2022.100570

• Deep learning-enabled medical computer vision

  npj Digital Medicine · 2021 · 10.1038/s41746-020-00376-2

• Prevalence of Asymptomatic SARS-CoV-2 Infection

  Annals of Internal Medicine · 2020 · 10.7326/m20-3012

• Artificial intelligence versus clinicians: systematic review of design, reporting standards, and claims of deep learning studies

  BMJ · 2020 · 10.1136/bmj.m689

• A comparison of deep learning performance against health-care professionals in detecting diseases from medical imaging: a systematic review and meta-analysis

  The Lancet Digital Health · 2019 · https://doi.org/10.1016/s2589-7500(19)30123-2

• High-performance medicine: the convergence of human and artificial intelligence

  Nature Medicine · 2018 · https://doi.org/10.1038/s41591-018-0300-7

• The personal and clinical utility of polygenic risk scores

  Nature Reviews Genetics · 2018 · 10.1038/s41576-018-0018-x

• State of Telehealth

  New England Journal of Medicine · 2016 · 10.1056/nejmra1601705

• Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease

  Nature · 2013 · https://doi.org/10.1038/nature12825

• Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci

  The American Journal of Human Genetics · 2012 · https://doi.org/10.1016/j.ajhg.2012.08.032

• Common variants in KCNN3 are associated with lone atrial fibrillation

  Nature Genetics · 2010 · https://doi.org/10.1038/ng.537

• Human genetic variation and its contribution to complex traits

  Nature Reviews Genetics · 2009 · 10.1038/nrg2554

• Patients With Prior Myocardial Infarction, Stroke, or Symptomatic Peripheral Arterial Disease in the CHARISMA Trial

  Journal of the American College of Cardiology · 2007 · https://doi.org/10.1016/j.jacc.2007.03.025

• Clopidogrel and Aspirin versus Aspirin Alone for the Prevention of Atherothrombotic Events

  New England Journal of Medicine · 2006 · https://doi.org/10.1056/nejmoa060989

• A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction

  Nature Genetics · 2005 · https://doi.org/10.1038/ng1692

• Abciximab as Adjunctive Therapy to Reperfusion in Acute ST-Segment Elevation Myocardial Infarction

  JAMA · 2005 · https://doi.org/10.1001/jama.293.14.1759

• Effect of Antihypertensive Agents on Cardiovascular Events in Patients With Coronary Disease and Normal Blood Pressure

  JAMA · 2004 · 10.1001/jama.292.18.2217

• The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke

  Nature Genetics · 2004 · 10.1038/ng1311

• Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy

  The Lancet · 2003 · 10.1016/s0140-6736(03)14232-8

• Bivalirudin and Provisional Glycoprotein IIb/IIIa Blockade Compared With Heparin and Planned Glycoprotein IIb/IIIa Blockade During Percutaneous Coronary Intervention

  JAMA · 2003 · 10.1001/jama.289.7.853

• Early and Sustained Dual Oral Antiplatelet Therapy Following Percutaneous Coronary Intervention

  JAMA · 2002 · https://doi.org/10.1001/jama.288.19.2411

• Comparison of Two Platelet Glycoprotein IIb/IIIa Inhibitors, Tirofiban and Abciximab, for the Prevention of Ischemic Events with Percutaneous Coronary Revascularization

  New England Journal of Medicine · 2001 · https://doi.org/10.1056/nejm200106213442502

• Sustained Ventricular Arrhythmias in Patients Receiving Thrombolytic Therapy

  Circulation · 1998 · https://doi.org/10.1161/01.cir.98.23.2567

• Myonecrosis After Revascularization Procedures

  Journal of the American College of Cardiology · 1998 · https://doi.org/10.1016/s0735-1097(97)00506-8

• Cardiac Troponin T Levels for Risk Stratification in Acute Myocardial Ischemia

  New England Journal of Medicine · 1996 · 10.1056/nejm199610313351801

• Our Preoccupation With Coronary Luminology

  Circulation · 1995 · 10.1161/01.cir.92.8.2333

• Coronary morphologic and clinical determinants of procedural outcome with angioplasty for multivessel coronary disease. Implications for patient selection. Multivessel Angioplasty Prognosis Study Group.

  Circulation · 1990 · 10.1161/01.cir.82.4.1193

Current projects

No projects listed.